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專家信息:
徐驍,男,浙江大學(xué)外科學(xué)教授、主任醫(yī)師、博士生導(dǎo)師。教育部“長江學(xué)者獎勵計劃”特聘教授、國家杰出青年科學(xué)基金獲得者、國家“**計劃”科技創(chuàng)新領(lǐng)軍人才、浙江大學(xué)求是特聘教授。 現(xiàn)任浙江大學(xué)醫(yī)學(xué)院副院長、附屬杭州市第一人民醫(yī)院院長、黨委副書記,浙江大學(xué)器官移植研究所副所長。長期從事肝膽胰外科和肝臟移植臨床工作,致力于移植腫瘤學(xué)及肝移植術(shù)后并發(fā)癥分子機制和防治新策略研究,在肝膽胰惡性腫瘤、肝內(nèi)外膽管結(jié)石等疾病臨床診治方面具有豐富經(jīng)驗。2001年及2006年先后赴香港大學(xué)醫(yī)學(xué)院外科學(xué)系瑪麗醫(yī)院和德國基爾大學(xué)外科分子腫瘤中心擔(dān)任訪問學(xué)者。作為項目負責(zé)人承擔(dān)863計劃課題、科技部重大專項課題、國家杰出青年科學(xué)基金、國家自然科學(xué)基金重點項目和多項省部級課題。以第一作者或通訊作者在Gut,J Hepatol等學(xué)術(shù)期刊發(fā)表SCI論文90余篇。作為副主編、編委編寫《臨床醫(yī)學(xué)導(dǎo)論》、《外科學(xué)》等多部國家級規(guī)劃教材和專著,作為主要完成人之一3次榮獲國家科技進步創(chuàng)新團隊獎、一等獎及二等獎,4次榮獲浙江省科學(xué)技術(shù)一等獎,是中國腫瘤青年科學(xué)家獎、吳孟超醫(yī)學(xué)青年基金獎獲得者。兼任中華醫(yī)學(xué)會器官移植學(xué)分會副主任委員兼肝移植學(xué)組組長、中國醫(yī)師協(xié)會器官移植醫(yī)師分會副會長兼總干事、中國抗癌協(xié)會腫瘤精準治療專業(yè)委員會副主任委員、浙江省抗癌協(xié)會腫瘤精準診治專業(yè)委員會主任委員、浙江省醫(yī)學(xué)會器官移植分會候任主任委員、浙江省醫(yī)師協(xié)會外科醫(yī)師分會副會長、美國外科醫(yī)師協(xié)會會員(FACS)等。
教育及工作經(jīng)歷:
1990年9月-1997年6月,于浙江醫(yī)科大學(xué)臨床醫(yī)學(xué)七年制專業(yè)學(xué)習(xí)。
1997年6月,獲浙江大學(xué)外科學(xué)(普外)碩士學(xué)位。
2002年6月,獲浙江大學(xué)外科學(xué)(普外)博士學(xué)位(科學(xué)型)。
1997年8月-1999年9月,任浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院肝膽胰外科助教、住院醫(yī)師。
1999年9月-2004年12月,任浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院肝膽胰外科講師、主治醫(yī)師。
2005年1月-至今,任浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院肝膽胰外科副教授、副主任醫(yī)師。
2010年1月-至今,任浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院肝膽胰外科主任醫(yī)師。
2001年9月-2002年9月,香港大學(xué)醫(yī)學(xué)院外科學(xué)系瑪麗醫(yī)院訪問學(xué)者。
2006年1月-2006年9月,德國基爾大學(xué)醫(yī)院外科分子腫瘤中心訪問學(xué)者。
學(xué)術(shù)兼職及社會任職:
1. 中華醫(yī)學(xué)會器官移植學(xué)分會副主任委員。
2. 中國醫(yī)師協(xié)會器官移植醫(yī)師分會常委兼總干事。
3. 中華醫(yī)學(xué)會外科學(xué)分會肝臟外科學(xué)組委員。
4. 中華醫(yī)學(xué)會微生物與免疫學(xué)分會移植免疫學(xué)組委員。
5. 中國研究型醫(yī)院學(xué)會移植醫(yī)學(xué)專業(yè)委員會副主任委員。
6. 全國醫(yī)師定期考核器官移植專業(yè)編輯委員會秘書長。
7. 中華醫(yī)學(xué)會器官移植學(xué)分會委員及學(xué)術(shù)秘書、肝移植學(xué)組委員。
8. 浙江省醫(yī)學(xué)會器官移植學(xué)分會委員。
9. 浙江省抗癌協(xié)會肝膽胰腫瘤專業(yè)委員會委員。
10. 浙江大學(xué)青年教授聯(lián)誼會副秘書長。
11. 《Hepatobiliary & Pancreatic Diseases International》(SCI收錄) 編委。
12. 《中華移植雜志(電子版)》 常務(wù)編委。
13. 《HBPD INT》 編委。
主講課程:
1、《外科學(xué)進展》
2、《外科學(xué)》
3、《外科學(xué)總論》
4、《臨床思維與技能訓(xùn)練》
5、《普通外科學(xué)專題》
6、《器官捐獻與器官移植》
培養(yǎng)研究生情況:
資料更新中……
研究方向:
1. 移植腫瘤學(xué) Transplant Oncology。
2. 肝膽胰惡性腫瘤精準診治 Precise Diagnosis and Treatment for Hepato-Pancreato-Biliary Malignancies。
3. 肝移植術(shù)后并發(fā)癥的分子機制與防治新策略 Underlying Mechanisms and Interventions of Complications after Liver Transplantation。
承擔(dān)科研項目:
主要從事肝膽胰外科和肝移植的臨床和基礎(chǔ)研究,在肝病和肝膽胰惡性腫瘤蛋白組學(xué)研究、肝移植預(yù)后預(yù)警體系及術(shù)后并發(fā)癥防治研究等領(lǐng)域取得多項創(chuàng)新性成果,是鄭樹森院士領(lǐng)導(dǎo)的肝膽胰外科和肝移植團隊的骨干核心成員,作為負責(zé)人承擔(dān)863計劃項目、973項目課題、國家科技重大專項課題、省部共建項目等多項國家級和省部級研究項目。
1. 肝病發(fā)生發(fā)展與肝癌轉(zhuǎn)移復(fù)發(fā)的蛋白質(zhì)分子標(biāo)志物的臨床應(yīng)用研究(國家高技術(shù)研究發(fā)展計劃(863計劃)課題)、2012-201511。
2. 乙肝相關(guān)肝癌肝移植臨床診療新體系研究及應(yīng)用推廣(“十三五”科技重大專項)、2017-2020
3. 肝移植原病復(fù)發(fā)的分子機制及防治研究(國家杰出青年科學(xué)基金)、2017-2021
4. 免疫代謝穩(wěn)態(tài)失衡在移植肝早期功能不全中的作用及機制研究(國自然重點項目)、2020-2024
5. 供肝LXR/SREBP/miR-33反饋環(huán)路調(diào)控脂質(zhì)代謝穩(wěn)態(tài)的作用及機制研究(國自然面上項目)、2016-2019
6. 免疫與基因治療新技術(shù)研究及藥物開發(fā)-基于新型核酸納米藥物調(diào)控免疫微環(huán)境的肝癌免疫治療新技術(shù)研究(浙江省重點研發(fā)項目),2019-2022
7. 新型納米材料靶向輸送技術(shù)的研發(fā)及其在肝癌治療中的應(yīng)用價值(浙江省重點研發(fā)項目)、2015-2018
8. 國家重點基礎(chǔ)研究發(fā)展計劃(973計劃)子課題,肝癌肝移植術(shù)后腫瘤復(fù)發(fā)的分子機制和預(yù)警研究。
9. 國家“十一五”科技支撐計劃子課題,“肝臟移植術(shù)后原發(fā)病復(fù)發(fā)的防治”項目子課題“肝癌肝移植術(shù)前受者準入標(biāo)準——“中國標(biāo)準”的制定”。
10. 衛(wèi)生部科學(xué)研究基金項目,基于PMPM評分的活體肝移植預(yù)后評估體系的建立和應(yīng)用。
11. 浙江省自然科學(xué)基金項目,移植肝臟基質(zhì)微環(huán)境的調(diào)控與腫瘤復(fù)發(fā)。
12. 浙江省中醫(yī)藥管理局重點項目研究計劃項目,中醫(yī)藥整體化應(yīng)用提升肝移植療效的臨床研究。
13. 浙江省科技廳項目,肝癌肝移植療效預(yù)測平臺的建立與臨床應(yīng)用。
14. 浙江省教育廳項目,肝癌肝移植受體選擇及預(yù)后預(yù)測體系的建立與應(yīng)用。
15. 浙江省衛(wèi)生廳項目,Cardiotrophin-1保護邊緣性移植肝臟功能的研究。
16. 浙江省衛(wèi)生廳項目,保護性基因誘導(dǎo)的肝臟與肝細胞聯(lián)合移植。
17. 浙江省中醫(yī)藥管理局項目,刺五加和穿心蓮內(nèi)酯對移植肝臟聯(lián)合保護作用的研究。
18. 國家自然科學(xué)基金面上項目,氨基酰化酶ACY1對肝癌侵襲轉(zhuǎn)移的調(diào)控作用及其機制研究
19. 國家科技重大專項課題,病毒性肝炎相關(guān)肝癌樣本庫的建設(shè)維護及基線水平調(diào)查
20. 國家自然科學(xué)基金創(chuàng)新群體,人工肝與肝移植治療終末期肝病的基礎(chǔ)應(yīng)用研究。
21. 國家重點基礎(chǔ)研究發(fā)展計劃(973計劃) ,器官移植的免疫學(xué)應(yīng)用基礎(chǔ)研究。
22. 省、市、自治區(qū)科技項目,移植肝臟基質(zhì)微環(huán)境的調(diào)控與腫瘤復(fù)發(fā),2009-12-31。
23. 提高肝移植病人長期存活率的臨床研究,20071231。
24. 脾切斷流術(shù)圍手術(shù)期低蛋白血癥臨床治療研究,20050601。
25. 免疫抑制劑FTY720抗肝癌的作用和機理研究,20061231。
26. 胰腺癌及癌周正常胰腺蛋白質(zhì)差異表達譜分析,20051231。
27. 省、市、自治區(qū)科技項目,肝癌肝轉(zhuǎn)移療效預(yù)測平臺的建立與臨床研究,2006-12-27。
28. 企事業(yè)單位委托科技項目,脾切斷流術(shù)低蛋白血癥,2005-06-23。
29. 乙肝相關(guān)性肝病肝移植術(shù)后乙肝復(fù)發(fā)的機制及干預(yù),20080831。
30. 肝移植術(shù)后乙肝復(fù)發(fā)預(yù)測平臺建立與應(yīng)用,20080831。
31. 浙醫(yī)一院項目,保護性基因誘導(dǎo)的肝臟與肝細胞聯(lián)合移植, 20051231。
32. 保護性基因轉(zhuǎn)導(dǎo)的肝臟與肝細胞聯(lián)合移植的實驗研究20031231
33. 省、市、自治區(qū)科技項目 ,保護性基因誘導(dǎo)的肝臟與肝細胞聯(lián)合移植,省、市、自治區(qū)科技項目 2005-12-25
34. 保護性基因轉(zhuǎn)導(dǎo)的肝臟與肝細胞聯(lián)合移植的實驗研究,省、市、自治區(qū)科技項目 2003-12-31
35. 浙醫(yī)一院項目,選擇性環(huán)氧合酶II抑制劑對胰腺癌細胞凋亡的實驗研究,20031231。
36. 不同體積肝移植中NF-KB及相關(guān)基因的作用研究,20031230。
科研成果:
1. 2002年,全國器官移植學(xué)術(shù)會議優(yōu)秀論文獎。
2. 2004年,教育部科技成果。
3. 2008年,國家科技進步二等獎(肝移植技術(shù)創(chuàng)新體系的建立與推廣應(yīng)用,9/15)
4. 2000年、2005年、2007年和2009年4項浙江省科技進步一等獎的項目主要完成者之一。
5. 2013年,國家科技進步一等獎(重癥肝病診治的理論創(chuàng)新與技術(shù)突破,7/15)
6. 榮獲浙江省醫(yī)藥衛(wèi)生科技創(chuàng)新一等獎。
6. 2005年、2007年和2009年3次榮獲浙江省科學(xué)技術(shù)一等獎。
7. 以第一作者發(fā)表100余篇學(xué)術(shù)論文(SCI收錄30篇),參編《外科學(xué)》(八年制/五年制)、《肝臟移植》、《胰腺移植》、《肝臟移植圍手術(shù)期處理》與《外科學(xué)進展》等多部著作和教材。以第一起草人撰寫《中國肝癌肝移植臨床實踐指南》和《中國心臟死亡捐獻器官評估與應(yīng)用專家共識》等行業(yè)指南與規(guī)范。
8. 863計劃”課題“肝病發(fā)生發(fā)展與肝癌轉(zhuǎn)移復(fù)發(fā)的蛋白質(zhì)分子標(biāo)志物的臨床應(yīng)用研究”,通過大量臨床分析和深入的機制研究,取得了一系列創(chuàng)新性成果:揭示了肝癌抑癌基因ACY1及其下游信號通路;發(fā)現(xiàn)肝癌血管侵犯相關(guān)分子標(biāo)志物CLIC1、PDI A6和APOA-Ⅰ,為臨床早期預(yù)測肝癌血管侵犯提供可能;確立了肝癌侵襲和轉(zhuǎn)移相關(guān)的基因TFCP2,進一步闡釋了肝癌發(fā)生發(fā)展過程中侵襲和轉(zhuǎn)移的分子機制。研究成果為肝癌分子分型奠定了重要理論基礎(chǔ),也為肝癌肝移植腫瘤復(fù)發(fā)防治提供了新的分子靶點。
9. 研究團隊運用材料學(xué)新技術(shù),使含寡精氨酸(Arg)序列的多肽與siRNA 形成穩(wěn)定的納米復(fù)合物,以前期研究發(fā)現(xiàn)的關(guān)鍵分子作為干預(yù)靶點,成功研發(fā)了生物相容性較高的體內(nèi)核酸藥物靶向輸送系統(tǒng),并通過體內(nèi)外實驗驗證了該納米核酸藥物傳遞技術(shù)具有優(yōu)異的靶向性。同時提出了抗癌藥物分子改造技術(shù)與兩親性高分子載藥系統(tǒng)相結(jié)合的新策略,如通過分子改造技術(shù)對SN-38分子不同位點進行化學(xué)修飾,成功構(gòu)建出全新的SN-38衍生物文庫,選出了具有高穩(wěn)定性及臨床應(yīng)用前景的納米藥物配方,并且證明了納米藥物的抗癌效果遠優(yōu)于現(xiàn)有臨床藥物伊立替康(SN-38 前藥),顯著提升了現(xiàn)有抗癌藥物的抑瘤效果。這一研究成果不僅提高了喜樹堿類衍生物SN-38的臨床應(yīng)用價值,而且也為其他抗癌藥物的改性提供了新的研究策略。
10. 研究團隊率先揭示供肝及其風(fēng)險基因在移植術(shù)后糖尿病中的作用機制,創(chuàng)新性地發(fā)現(xiàn)了供者TCF7L2基因參與肝移植受者糖尿病發(fā)生的機制,供肝TCF7L2基因rs290487位點突變是PTDM 的獨立危險因素。這意味著,檢測供肝TCF7L2基因多態(tài)性可以顯著提高臨床模型的預(yù)警能力,有利于在早期預(yù)警糖尿病的發(fā)生,及早采用個性化的用藥方案,從而實現(xiàn)PTDM的有效防治。這項創(chuàng)新性研究成果在《Journal of Hepatology》一經(jīng)發(fā)表,便獲得了學(xué)界的廣泛關(guān)注。
11. 建立了移植術(shù)后乙肝復(fù)發(fā)預(yù)警MERB模型,其敏感性達到87.5%,顯著減少了昂貴的免疫球蛋白使用,避免了不必要的醫(yī)療資源耗費。這項研究結(jié)果發(fā)表于肝病研究權(quán)威雜志《Liver International》,引起了國際學(xué)術(shù)界的廣泛關(guān)注。《Liver International》雜志撰寫述評認為:“該研究為慢性乙肝患者肝移植手術(shù)的預(yù)后帶來了光明的前景。”該研究成果已推廣應(yīng)用于四川大學(xué)華西醫(yī)院等十余家國內(nèi)知名肝移植中心,臨床效果受到了一致肯定。
12. 研究發(fā)現(xiàn),相比米蘭標(biāo)準,杭州標(biāo)準安全有效的增加了51.5%的移植受者。NRI分析和AUROC表明,相對米蘭標(biāo)準和UCSF標(biāo)準,杭州標(biāo)準能更好的預(yù)測移植后肝癌復(fù)發(fā),驗證了杭州標(biāo)準相對國際其他標(biāo)準的優(yōu)勢。對于超越米蘭標(biāo)準但符合杭州標(biāo)準的受者,AFP(甲胎蛋白)>100ng/mL和腫瘤直徑>8cm是兩個獨立性預(yù)后預(yù)測因子。進而將杭州標(biāo)準分為A型(腫瘤直徑≤8cm,或者腫瘤直徑>8cm但AFP≤100ng/mL) 和B型(腫瘤直徑>8cm但AFP在100和400ng/mL之間),其中A型受者5年無瘤生存率高達69.5%,是最適宜行肝移植的肝癌亞群。該研究所建立的預(yù)后評判體系,可實現(xiàn)肝移植受者有效篩選,指導(dǎo)個性化治療。成果發(fā)表于消化領(lǐng)域頂級期刊《Gut》。
發(fā)明公開:
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發(fā)明授權(quán):
[1]徐驍, 楊墨丹, 魯?shù)? 汪國營, 莊莉, 楊揚. 一種用于評估超米蘭標(biāo)準肝癌患者肝移植后腫瘤復(fù)發(fā)風(fēng)險的試劑盒[P]. 浙江省: CN113791218B, 2023-05-23.
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[3]徐驍, 王建國, 陶耀業(yè), 相佳佳, 柯慶宏, 申有青. 一種缺氧響應(yīng)的陽離子聚合物及其制備方法和應(yīng)用[P]. 浙江省: CN112574343B, 2021-10-15.
[4]徐驍, 相佳佳, 陶耀業(yè), 王建國, 申有青, 柯慶宏, 岑貝妮. 一種氧化響應(yīng)去電荷的陽離子聚合物及其制備方法和應(yīng)用[P]. 浙江省: CN112574344B, 2021-10-15.
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[6]王杭祥, 陳建美, 李玲玲, 謝海洋, 周琳, 徐驍, 鄭樹森. iRGD-抗癌藥物偶聯(lián)物及其制備方法和應(yīng)用[P]. 浙江省: CN105396141B, 2018-08-24.
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代表性英文論文:
[1]Feng, Tingting; Ling, Sunbin; Xu, Chenyang; Ying, Lisha; Su, Dan*; Xu, Xiao*.Ubiquitin-specific peptidase 22 in cancer.Cancer Letters, 2021, 514: 30-37.
[2]Yu, Jiong; Shi, Xiaowei; Ma, Jing; Chen, Ronggao; Dong, Siyi; Lu, Sen; Wu, Jian; Yan, Cuilin; Zheng, Shusen; Li, Lanjuan; Xu, Xiao*; Cao, Hongcui*.C-Reactive Protein Is an Independent Predictor of 30-Day Bacterial Infection Post-Liver Transplantation.Biomolecules, 2021, 11(8): 1195.
[3]Pan, Binhua; Yang, Modan; Wei, Xuyong; Li, Wangyao; Wang, Kun; Yang, Mengfan; Lu, Di; Wang, Rui; Cen, Beini; Xu, Xiao*.Interleukin-2 inducible T-cell kinase: a potential prognostic biomarker and tumor microenvironment remodeling indicator for hepatocellular carcinoma.Aging-US, 2021, 13(14): 18620-18644.
[4]He, Zeng-Lei; Zhou, Jun-Bin; Liu, Zhi-Kun; Dong, Si-Yi; Zhang, Yun-Tao; Shen, Tian; Zheng, Shu-Sen; Xu, Xiao*.Application of machine learning models for predicting acute kidney injury following donation after cardiac death liver transplantation.Hepatobiliary and Pancreatic Diseases International, 2021, 20(3): 222-231.
[5]Fan, Guanghan; Zhang, Chenzhi; Wei, Xuyong; Wei, Rongli; Qi, Zhetuo; Chen, Kangchen; Cai, Xuechun; Xu, Li; Tang, Linsong; Zhou, Junbin; Zhang, Zhensheng; Lin, Zuyuan; Xie, Haiyang; Zheng, Shusen; Fan, Weimin; Xu, Xiao*.NEAT1/hsa-miR-372?3p axis participates in rapamycin-induced lipid metabolic disorder.Free Radical Biology and Medicine, 2021, 167: 1-11.
[6]Ding, Ning; Xu, Shengjun; Zheng, Sheng; Ye, Qianwei; Xu, Li; Ling, Sunbin; Xie, Shanshan; Chen, Wenwen; Zhang, Zizhen; Xue, Meng; Lin, Zhenghua; Xu, Xiao*; Wang, Liangjing*."Sweet tooth"-oriented SN38 prodrug delivery nanoplatform for targeted gastric cancer therapy.Journal of Materials Chemistry B, 2021, 9(12): 2816-2830.
[7]Wang, Kun; Lu, Di; Liu, Yuhui; Li, Wangyao; Zhuang, Li; Ma, Zhenyu; Xie, Qinfen; Pan, Binhua; Wu, Yichao; Chen, Junli; Lin, Lidan; Feng, Xiaowen; Wei, Qiang; Wei, Xuyong; Xie, Haiyang; Wang, Zhengxin*; Zheng, Shusen*; Xu, Xiao*.Severity of early allograft dysfunction following donation after circulatory death liver transplantation: a multicentre study.Hepatobiliary Surgery and Nutrition, 2021, 10(1): 9-19.
[8]Wang, Chao; Zhang, Xueyou; Ling, Qi; Zheng, Shusen*; Xu, Xiao*.A model integrating donor gene polymorphisms predicts fibrosis after liver transplantation.Aging-US, 2021, 13(1): 1264-1275.
[9]Wang, Dan-Yang; He, Kang-Xin; Huang, Ying; Lou, Qin-Qin; He, Ti; Xu, Xiao*.A New Method for the Detection of Colorectal Cancer and the Precancerous Lesions: Occult Blood Testing Combination with Promoter Methylation in the Fecal Sample.Journal of Cancer, 2021, 12(2): 335-342.
[10]Zhang, Chenzhi; Chen, Kangchen; Wei, Rongli; Fan, Guanghan; Cai, Xuechun; Xu, Li; Cen, Beini T.; Wang, Jianguo; Xie, Haiyang; Zheng, Shusen; Xu, Xiao*. The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis. Signal Transduction and Targeted Therapy, 2020, 5(1): 23. (IF=13.493)
[11]Tang, Linsong#; Chen, Ronggao#; Xu, Xiao*. Synthetic lethality: A promising therapeutic strategy for hepatocellular carcinoma. Cancer Letters, 2020, 476(2020): 120-128.(IF=7.36)
[12]Wei, Qiang; Zhou, Junbin; Shen, Tian; Zheng, Shusen; Xu, Xiao*. Coronavirus disease 2019: implications for liver transplantation. Hepatobiliary Surgery and Nutrition, 2020, 9(3): 325-329. (IF=5.296)
[13]Lin Z, Lu D, Wei X, Wang J, Xu X*. Heterogeneous responses in hepatocellular carcinoma: the achilles heel of immune checkpoint inhibitors. Am J Cancer Res. 2020 Apr;10(4):1085-1102. (IF=5.177)
[14]Lin, Zuyuan; Xiang, Xiaonan; Lu, Di; Xu, Xiao*.Targeting tumor microenvironment as a treatment strategy for hepatocellular carcinoma.Hepatobiliary Surgery and Nutrition, 2020, 9(6): 794-796.
[15]Zhuo, Jianyong; Su, Renyi; Tan, Winyen; Lian, Zhengxing; Lu, Di; Xu, Xiao*.The ongoing trends of patient-derived xenograft models in oncology.Cancer Communications, 2020, 40(11): 559-563.
[16]Yaoye, Tao; Shengjun, Xu; Jianguo, Wang; Li, Xu; Chenzhi, Zhang; Kangchen, Chen; Zhengxing, Lian; Junbin, Zhou; Haiyang, Xie; Shusen, Zheng; Xiao, Xu.Delivery of microRNA-33 Antagomirs by Mesoporous Silica Nanoparticles to Ameliorate Lipid Metabolic Disorders.Frontiers in Pharmacology, 2020, 11.
[17]Zhan, Qi-Fan; Ling, Sun-Bin; Deng, Yi-Nan; Shan, Qiao-Nan; Ye, Qian-Wei; Xu, Sheng-Jun; Jiang, Guang-Jiang; Lu, Di; Wei, Xu-Yong; Zhuang, Li; Zhang, Wu; Shen, Tian; Cen, Bei-Ni; Xie, Hai-Yang; Liu, Ji-Min; Wu, Jian; Zheng, Shu-Sen*; Yang, Yang*; Xu, Xiao*.Hangzhou criteria as downstaging criteria in hepatocellular carcinoma before liver transplantation: A multicenter study from China.Hepatobiliary and Pancreatic Diseases International, 2020, 19(4): 349-357.
[18]Shen, Tian; Zhuang, Li; Sun, Xiao-Dong; Qi, Xiao-Sheng; Wang, Zhi-Hui; Li, Rui-Dong; Chang, Wen-Xiu; Yang, Jia-Yin; Yang, Yang; Zheng, Shu-Sen; Xu, Xiao*.Expert consensus on management of metabolic disease in Chinese liver transplant recipients.World Journal of Gastroenterology, 2020, 26(27): 3851-3864.
[19]Ling, Sunbin; Shan, Qiaonan; Zhan, Qifan; Ye, Qianwei; Liu, Peng; Xu, Shengjun; He, Xin; Ma, Jian; Xiang, Jiajia; Jiang, Guangjiang; Wen, Xue; Feng, Zijie; Wu, Yuan; Feng, Tingting; Xu, Li; Chen, Kangchen; Zhang, Xuanyu; Wei, Rongli; Zhang, Chenzhi; Cen, Beini; Xie, Haiyang; Song, Penghong; Liu, Jimin; Zheng, Shusen; Xu, Xiao.USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1 alpha/USP22 positive feedback loop upon TP53 inactivation.Gut, 2020, 69(7): 1322-1334.
[20]Lu, Di; Yang, Fan; Zhuo, Jianyong; Yang, Modan; Lin, Zuyuan; Jin, Pingbo; Cai, Xuechun; Cen, Beini; Wang, Jianguo; Wei, Xuyong; Zheng, Shusen; Xu, Xiao*.The Matching Status Between Donor and Recipient Hepatitis B Seroepidemiology Makes a Difference in Liver Transplantation for Hepatocellular Carcinoma.Clinical and Translational Gastroenterology, 2020, 11(5): e00168.
[21]Wen, Xue; Ling, Sunbin; Wu, Weiqiang; Shan, Qiaonan; Liu, Peng; Wang, Chao; Wei, Xuyong; Ding, Wei; Teng, Xiaodong; Xu, Xiao*.Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma.Digestive Diseases and Sciences, 2020, 65(4): 1064-1073.
[22]Wei, Qiang; He, Zenglei; Wang, Kun; Li, Changbiao; Al Ameri, Abdulahad; Zheng, Shusen; Xu, Xiao*.Prediction model based on blood urea nitrogen and the leukocyte count for intestinal necrosis in patients with portal vein system thrombosis: a retrospective study.Annals of Translational Medicine, 2020, 8(6): 326.
[23]Yang, Zhentao; Zhu, Hai; Zhang, Liang; Wei, Qiang; Zhou, Lin; Xu, Xiao; Song, Penghong; Liu, Jialin; Xie, Haiyang*; Zheng, Shusen*.DNA methylation of SOCS1/2/3 predicts hepatocellular carcinoma recurrence after liver transplantation.Molecular Biology Reports, 2020, 47(3): 1773-1782.
[24]Shen, Xiaoyong; Yang, Fan; Yang, Pengfei; Yang, Modan; Xu, Lei; Zhuo, Jianyong; Wang, Jianguo; Lu, Di; Liu, Zhikun; Zheng, Shu-sen; Niu, Tianye*; Xu, Xiao*.A Contrast-Enhanced Computed Tomography Based Radiomics Approach for Preoperative Differentiation of Pancreatic Cystic Neoplasm Subtypes: A Feasibility Study.Frontiers in Oncology, 2020, 10: 248.
[25]Liu, Peng; Lu, Di; Al-ameri, Abdulahad; Wei, Xuyong; Ling, Sunbin; Li, Jie; Zhu, Hai; Xie, Haiyang; Zhu, Liming; Zheng, Shusen; Xu, Xiao*.Glutamine synthetase promotes tumor invasion in hepatocellular carcinoma through mediating epithelial-mesenchymal transition.Hepatology Research, 2020, 50(2): 246-257.
[26]Ling, Sunbin; Feng, Tingting; Zhan, Qifan; Duan, Xin; Jiang, Guangjiang; Shen, Tian; Shan, Qiaonan; Xu, Shengjun; Ye, Qianwei; Liu, Peng; Cen, Beini; Zhen, Shusen; Xu, Xiao*.Sirolimus-based immunosuppression improves outcomes in liver transplantation recipients with hepatocellular carcinoma beyond the Hangzhou criteria.Annals of Translational Medicine, 2020, 8(4): 80.
[27]Wang, Kun; Wei, Xuyong; Wei, Qiang; Lu, Di; Li, Wangyao; Pan, Binhua; Chen, Junli; Xie, Haiyang; Zheng, Shusen; Xu, Xiao.A two-circular RNA signature of donor circFOXN2 and circNECTIN3 predicts early allograft dysfunction after liver transplantation.Annals of Translational Medicine, 2020, 8(4): 94.
[28]Zhuo, Jian-Yong; Lu, Di; Lin, Zu-Yuan; Cen, Bei-Ni; Wei, Xu-Yong; Xie, Hai-Yang; Zheng, Shu-Sen; Xu, Xiao*.CC motif chemokine ligand 16 inhibits the progression of liver cirrhosis via inactivating hepatic stellate cells.Hepatobiliary and Pancreatic Diseases International, 2020.
[29]Yang, Modan; Tan, Winyen; Yang, Xinyu; Zhuo, Jianyong; Lin, Zuyuan; Cen, Beini; Lian, Zhengxing; Li, Huihui; Lu, Di; Wei, Xuyong; Zheng, Shusen; Xu, Xiao*.Homocysteine: A novel prognostic biomarker in liver transplantation for alpha-fetoprotein-negative hepatocellular carcinoma.Cancer Biomarkers, 2020, 29(2): 197-206.
[30]Wang, Jianguo; Zhuo, Jianyong; Tao, Yaoye; Xu, Shengjun; Chen, Zun; Yang, Fan; Ke, Qinghong; Xie, Haiyang; Zheng, Shusen; Wang, Hangxiang; Xu, Xiao*.Salinomycin-Loaded Small-Molecule Nanoprodrugs Enhance Anticancer Activity in Hepatocellular Carcinoma.International Journal of Nanomedicine, 2020, 15: 6839-6854.
[31]Chen, Ronggao; Cheng, Qiyang; Owusu-Ansah, Kwabena Gyabaah; Song, Guangyuan; Jiang, Donghai; Zhou, Lin; Xu, Xiao; Wu, Jian*; Zheng, Shusen*.NKILA, a prognostic indicator, inhibits tumor metastasis by suppressing NF-kappa B/Slug mediated epithelial-mesenchymal transition in hepatocellular carcinoma.International Journal of Biological Sciences, 2020, 16(3): 495-503.
[32]Zhu, Hai; Yang, Zhentao; Zhao, Xinyi; Zhang, Liang; Ren, Zhigang; Zhou, Ke; Song, Penghong; Xu, Xiao; Xie, Haiyang*; Zheng, Shusen*.pSTAT3 Y705 is a prognostic biomarker identified from time-series gene expression profiles of a chemically induced mouse model of hepatocellular carcinoma.American Journal of Translational Research, 2020, 12(4): 1443-+.
[33]Ling S, Shan Q, Zhan Q, Zheng S*, Xu X*. USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation. Gut. 2019; gutjnl-2019-319616. (IF=19.819)
[34]Ye, Qianwei; Ling, Sunbin; Zheng, Shusen*; Xu, Xiao*. Liquid biopsy in hepatocellular carcinoma: Circulating tumor cells and circulating tumor DNA. Molecular Cancer, 2019, 18(1): UNSP 114. (IF=15.302)
[35]Li, Changbiao; Xu, Xiao*. Biological functions and clinical applications of exosomal non-coding RNAs in hepatocellular carcinoma. Cellular and Molecular Life Sciences, 2019, 76(21): 4203-4219.. (IF=6.496)
[36]Wang K, Lu D, Liu Y, Zheng S*, Xu X*. Severity of early allograft dysfunction following donation after circulatory death liver transplantation: a multicenterstudy. HepatoBiliary Surg. Nutr. 2019; [Epub]. (IF=5.296)
[37]Jia, Jun-Jun; Li, Jian-Hui; Xin, Liming; Li, Hao-Yu; Badiwala, Mitesh; Sun, Yu; Xu, Xiao; Zheng, Shu-Sen*.International Organ Protection Symposium: The fusion of engineering and medicine.Hepatobiliary and Pancreatic Diseases International, 2019, 18(6): 601-602.
[38]Lu, Di; Yang, Fan; Lin, Zuyuan; Zhuo, Jianyong; Liu, Peng; Cen, Beini; Lian, Zhengxing; Xie, Haiyang; Zheng, Shusen; Xu, Xiao*.A prognostic fingerprint in liver transplantation for hepatocellular carcinoma based on plasma metabolomics profiling.European Journal of Surgical Oncology, 2019, 45(12): 2347-2352.
[39]Al-Ameri, Abdulahad Abdulrab Mohammed; Wei, Xuyong; Lin, Lidan; Shao, Zhou; Guo, Haijun; Xie, Haiyang; Zhou, Lin; Zheng, Shusen; Xu, Xiao*.Preoperative risk stratification for early recurrence of HBV-related hepatocellular carcinoma after deceased donor liver transplantation: a five-eight model development and validation.BMC Cancer, 2019, 19(1): 1136.
[40]Zhou, Junbin; Wei, Qiang; Zheng, Shusen; Xu, Xiao*.Early allograft dysfunction after liver transplantation with donation after cardiac death donors.Hepatobiliary Surgery and Nutrition, 2019, 8(5): 566-568.
[41]Al Ameri, Abdulahad Abdulrab Mohammed; Wei, Xuyong; Liu, Peng; Lin, Lidan; Shao, Zhou; Xie, Haiyang; Zhou, Lin; Zheng, Shusen; Xu, Xiao*.Prediction of Early Recurrence of Hepatocellular Carcinoma in Patients with Cirrhosis Who Had Received Deceased Donor Liver Transplantation: A Multicenter Study.Annals of Transplantation, 2019, 24: 489-498.
[42]Xu, Xiao*; Chen, Jun; Wei, Qiang; Liu, Zhi Kun; Yang, Zhe; Zhang, Ming; Wang, Guo Ying; Gao, Jie; Yang, Zhao Xu; Guo, Wen Yuan; Xing, Tong Hai; Shao, Zhou; Xie, Qin Fen; Zheng, Shu Sen*.Clinical practice guidelines on liver transplantation for hepatocellular carcinoma in China (2018 edition).Hepatobiliary and Pancreatic Diseases International, 2019, 18(4): 307-312.
[43]Guo, Hai Jun; Wang, Kun; Chen, Kang Chen; Liu, Zhi Kun; Al Ameri, Abdulahad; Shen, Yan; Xu, Xiao; Zheng, Shu Sen*.Middle hepatic vein reconstruction in adult right lobe living donor liver transplantation improves recipient survival.Hepatobiliary and Pancreatic Diseases International, 2019, 18(2): 125-131.
[44]Wang, Chao; Lu, Di; Ling, Qi; Chen, Jun; Liu, Zhikun; Guo, Haijun; Xu, Xiao*; Zheng, Shusen*.Donor one-carbon metabolism gene single nucleotide polymorphisms predict the susceptibility of cancer recurrence after liver transplantation.Gene, 2019, 689: 97-101.
[45]Zhuang, Runzhou; Zhang, Xuanyu; Lu, Di; Wang, Jianguo; Zhuo, Jianyong; Wei, Xuyong; Ling, Qi; Xie, Haiyang; Zheng, Shusen*; Xu, Xiao*.lncRNA DRHC inhibits proliferation and invasion in hepatocellular carcinoma via c-Myb-regulated MEK/ERK signaling.Molecular Carcinogenesis, 2019, 58(3): 366-375.
[46]Zhang, Xuanyu; Zhuang, Runzhou; Ye, Qianwei; Zhuo, Jianyong; Chen, Kangchen; Lu, Di; Wei, Xuyong; Xie, Haiyang; Xu, Xiao*; Zheng, Shusen*.High Expression of Human AugminComplex Submit 3 Indicates Poor Prognosis and Associates with Tumor Progression in Hepatocellular Carcinoma.Journal of Cancer, 2019, 10(6): 1434-1443.
[47]Chen, Ronggao; Qiao, Yiting; Hu, Wendi; Cheng, Qiyang; Xie, Haiyang; Zhou, Lin; Xu, Xiao; Zheng, Shusen*; Jiang, Donghai*.LY2228820 induces synergistic anti-cancer effects with anti-microtubule chemotherapeutic agents independent of P-glycoprotein in multidrug resistant cancer cells.American Journal of Cancer Research, 2019, 9(10): 2216-2232.
[48]Liu, Zhikun; Ye, Qianwei; Wu, Lingjiao; Gao, Feng; Xie, Haiyang; Zhou, Lin; Zheng, Shusen*; Xu, Xiao*.Metallothionein 1 family profiling identifies MT1X as a tumor suppressor involved in the progression and metastastatic capacity of hepatocellular carcinoma.Molecular Carcinogenesis, 2018, 57(11): 1435-1444.
[49]Qu, Zhi; Ling, Qi; Gwiasda, Jill; Xu, Xiao*; Schrem, Harald*; Beneke, Jan; Kaltenborn, Alexander; Krauth, Christian; Mix, Heiko; Klempnauer, Jurgen; Emmanouilidis, Nikos.Hangzhou criteria are more accurate than Milan criteria in predicting long-term survival after liver transplantation for HCC in Germany.Langenbecks Arch Surg, 2018, 403(5): 643-654.
[50]Lu, Di; Zhuo, Jianyong; Yang, Modan; Wang, Chao; Pan, Linhui; Xie, Haiyang; Xu, Xiao*; Zheng, Shusen*.The association between donor genetic variations in one-carbon metabolism pathway genes and hepatitis B recurrence after liver transplantation.Gene, 2018, 663: 121-125.
[51]Ling Qi; Liu Jimin; Zhuo Jianyong; Zhuang Runzhou; Huang Haitao; He Xiangxiang; Xu Xiao; Zheng Shusen*.Development of models to predict early post-transplant recurrence of hepatocellular carcinoma that also integrate the quality and characteristics of the liver graft: A national registry study in China.Surgery, 2018, 164(1): 155-164.
[52]Wei Qiang; Wang Kun; He Zenglei; Ke Qinghong; Xu Xiao*; Zheng Shusen.Acute Liver Allograft Rejection After Living Donor Liver Transplantation: Risk Factors and Patient Survival.American Journal of the Medical Sciences, 2018, 356(1): 23-29.
[53]Lu Di; Wang Wei; Liu Jingfeng; Qi Ling; Zhuang Runzhou; Zhuo Jianyong; Zhang Xuanyu; Xu Xiao; Zheng Shusen.Peroxiredoxins in inflammatory liver diseases and ischemic/reperfusion injury in liver transplantation.Food and Chemical Toxicology, 2018, 113: 83-89.
[54]Liu Zhikun; Li Jie; Chen Jun; Shan Qiaonan; Dai Haojiang; Xie Haiyang; Zhou Lin; Xu Xiao; Zheng Shusen.MCM family in HCC: MCM6 indicates adverse tumor features and poor outcomes and promotes S/G2 cell cycle progression.BMC Cancer, 2018, 18(1): 200.
[55]Xu L, Xu S, Wang H, Zheng S*, Xu X*. Enhancing the Efficacy and Safety of Doxorubicin against Hepatocellular Carcinoma through a Modular Assembly Approach: The Combination of Polymeric Prodrug Design, Nanoparticle Encapsulation, and Cancer Cell-Specific Drug Targeting. ACS Appl Mater Interfaces. 2018;10(4): 3229-40. (IF=8.758)
[56]Wang, Hangxiang*; Zhou, Liqian; Xie, Ke; Wu, Jiaping; Song, Penghong; Xie, Haiyang; Zhou, Lin; Liu, Jialin; Xu, Xiao; Shen, Youqing; Zheng, Shusen*.Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma.Theranostics, 2018, 8(14): 3949-3963.
[57]Wang, Hangxiang*; Lu, Zhongjie; Wang, Lijiang; Guo, Tingting; Wu, Jiaping; Wan, Jianqin; Zhou, Liqian; Li, Hui; Li, Zhen; Jiang, Donghai; Song, Penghong; Xie, Haiyang; Zhou, Lin; Xu, Xiao; Zheng, Shusen*.New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity.Cancer Research, 2017, 77(24): 6963-6974.
[58]Zhuang Runzhou; Lu Di; Zhuo Jianyong; Zhang Xuanyu; Wang Kun; Wei Xuyong; Wei Qiang; Wang Wei; Xie Haiyang; Zhou Lin; Xu Xiao*; Zheng Shusen*.CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-beta-mediated epithelial-mesenchymal transition in hepatocellular carcinoma.Oncotarget, 2017, 8(55): 94759-94768.
[59]Ling Sunbin; Shan Qiaonan; Liu Peng; Feng Tingting; Zhang Xuanyu; Xiang Penghui; Chen Kangchen; Xie Haiyang; Song Penghong; Zhou Lin; Liu Jimin; Zheng Shusen*; Xu Xiao*.Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I.Cell Death & Disease, 2017, 8(11): e3159.
[60]Wang Dan Yang; Ye Feng; Lin Jian Jiang; Xu Xiao*.Cutaneous metastasis: a rare phenomenon of colorectal cancer.Annals of Surgical Treatment and Research, 2017, 93(5): 277-280.
[61]Fu Yan; Xu Xiao; Huang Dongsheng; Cui Dawei; Liu Lisheng; Liu Junwei; He Zenglei; Liu Jingjing; Zheng Shusen*; Luo Yongzhang*.Plasma Heat Shock Protein 90alpha as a Biomarker for the Diagnosis of Liver Cancer: An Official, Large-scale, and Multicenter Clinical Trial.EBioMedicine, 2017, 24: 56-63.
[62]Wei Qiang; Gao Feng; Zhuang Runzhou; Ling Qi; Ke Qinghong; Wu Jian; Shen Tian; Zhang Mangli; Zhang Min; Xu Xiao*; Zheng Shusen*..A national report from China Liver Transplant Registry: steroid avoidance after liver transplantation for hepatocellular carcinoma.Chinese Journal of Cancer Research, 2017, 29(5): 426-437.
[63]Ling, Sunbin; Li, Jie; Shan, Qiaonan; Dai, Haojiang; Lu, Di; Wen, Xue; Song, Penghong; Xie, Haiyang; Zhou, Lin; Liu, Jimin; Xu, Xiao*; Zheng, Shusen*.USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway.MOLECULAR ONCOLOGY, 2017, 11(6): 682-695.
[64]Wei Qiang; Nemdharry Rahmeet Singh; Zhuang Run Zhou; Li Jie; Wu Ling Jian; Shen Tian; Zhou Lin; Xie Hai Yang; Zhang Min; Xu Xiao; Zheng Shu Sen*.A good prognostic predictor for liver transplantation recipients with benign end-stage liver cirrhosis.Hepatobiliary and Pancreatic Diseases International, 2017, 16(2): 164-168.
[65]Ling Qi; Xu Xiao; Ye Panpan; Xie Haiyang; Gao Feng; Hu Qichao; Liu Zhikun; Wei Xuyong; Roeder Christian; Trauzold Anna; Kalthoff Holger*; Zheng Shusen*.The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma.Oncotarget, 2017, 8(9): 15159-15167.
[66]Ling Qi; Dai Haojiang; Zhuang Runzhou; Shen Tian; Wang Weilin; Xu Xiao*; Zheng Shusen*.Predicting short-term survival after liver transplantation on eight score systems: a national report from China Liver Transplant Registry.Scientific Reports, 2017, 7(1): 42253.
[67]Xia Weiliang; Ke Qinghong; Guo Hua; Wang Weilin; Zhang Min; Shen Yan; Wu Jian; Xu Xiao; Yan Sheng; Yu Jun; Zhang Mangli; Zheng Shusen*.Expansion of the Milan criteria without any sacrifice: combination of the Hangzhou criteria with the pre-transplant platelet-to-lymphocyte ratio.BMC Cancer, 2017, 17(1): 14.
[68]Ling Q; Xie H; Li J; Liu J; Cao J; Yang F; Wang C; Hu Q; Xu X; Zheng S.Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation.American Journal of Transplantation, 2017, 17(1): 255-264.
[69]Liu Zhikun; Gao Feng; Shao Zhou; Xie Haiyang; Zhou Lin; Xu Xiao*; Zheng Shusen*.TFCP2 Genetic Polymorphism Is Associated with Predisposition to and Transplant Prognosis of Hepatocellular Carcinoma.Gastroenterology Research and Practice, 2017, 2017: 6353248.
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[71]Ling Q; Xie H; Li J; Xu X*; Zheng S*. Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation. Am J Transplant. 2017;17(1):255-264. (IF=7.338)
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[73]Xu, Xiao; Lu, Di; Zhuang, Runzhou; Wei, Xuyong; Xie, Haiyang; Wang, Chao; Zhu, Yangbo; Wang, Jianguo; Zhong, Cheng; Zhang, Xuanyu; Wei, Qiang; He, Zenglei; Zhou, Lin; Zheng, Shusen*.The phospholipase A2 activity of peroxiredoxin 6 promotes cancer cell death induced by tumor necrosis factor alpha in hepatocellular carcinoma.Molecular Carcinogenesis, 2016, 55(9): 1299-1308.
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[75]Xu, Xiao; Liu, Zhikun; Wang, Jianguo; Ling, Qi; Xie, Haiyang; Guo, Haijun; Wei, Xuyong; Zhou, Lin; Zheng, Shusen*.miRNA profiles in livers with different mass deficits after partial hepatectomy and miR-106b similar to 25 cluster accelerating hepatocyte proliferation in rats.Scientific Reports, 2016, 6: 31267.
[76]Zhong Cheng; Shanqiaonan; Zhuang Runzhou; Zhou Lin; Xu Xiao; Zheng ShuSen*.3D Printing of Differentiated Bone Marrow Mesenchymal Cells as a New Method for Liver Tissue Engineering.Journal of Biomaterials and Tissue Engineering, 2016, 6(8): 642-648.
[77]Zhong Cheng; Zhuang Runzhou; Xie HaiYang; Zhou Lin; Xu Xiao; Zheng ShuSen*.Hepatocyte Growth Factor-Loaded Collagen-Chitosan Scaffold Containing Differentiated Bone Marrow-Derived Mesenchymal Stem Cells as a Model for Hepatic Tissue Engineering.Journal of Biomaterials and Tissue Engineering, 2016, 6(8): 621-628.
[78]Wei, Qiang; Xu, Xiao; Wang, Chao; Zhuang, Runzhou; Zhuang, Li; Zhou, Lin; Xie, Haiyang; Wu, Jian; Zhang, Min; Shen, Yan; Wang, Weilin; Zheng, Shusen*.Efficacy and Safety of a Steroid-Free Immunosuppressive Regimen after Liver Transplantation for Hepatocellular Carcinoma.Gut and Liver, 2016, 10(4): 604-610.
[79]Tu, Z.; Xiang, P.; Xu, X.; Zhou, L.; Zhuang, L.; Wu, J.; Wang, W.*; Zheng, S.*.DCD liver transplant infection: experience from a single centre in China.International Journal of Clinical Practice, 2016, 70: 3-10.
[80]Zhang, W.; Zhong, H.; Zhuang, L.; Yu, J.; Xu, X.; Wang, W.; Zhang, M.; Zhou, L.; Zheng, S.*.Peripheral blood CD4(+) cell ATP activity measurement to predict HCC recurrence post-DCD liver transplant.International Journal of Clinical Practice, 2016, 70: 11-16.
[81]Ling, Qi; Xu, Xiao; Xie, Haiyang; Wang, Kai; Xiang, Penghui; Zhuang, Runzhou; Shen, Tian; Wu, Jian; Wang, Weilin; Zheng, Shusen*.New-onset diabetes after liver transplantation: a national report from China Liver Transplant Registry.Liver International, 2016, 36(5): 705-712.
[82]Ling, Qi; Xu, Xiao; Wang, Baohong; Li, Lanjuan*; Zheng, Shusen*.The Origin of New-Onset Diabetes After Liver Transplantation: Liver, Islets, or Gut?Transplantation, 2016, 100(4): 808-813.
[83]He, Zeng-Lei; Xu, Xiao; Ke, Qing-Hong; Zheng, Shu-Sen*.Successful diagnosis of intrahepatic splenosis mimicking hepatic tumor.The Kaohsiung Journal of Medical Sciences, 2016, 32(4): 224-225.
[84]Xu, Xiao; Liu, Zhikun; Wang, Jianguo; Xie, Haiyang; Li, Jie; Cao, Jili; Zhou, Lin; Zheng, Shusen*.Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma.Oncotarget, 2016, 7(12): 13730-13741.
[85]Wang, Jianguo; Xie, Haiyang; Ling, Qi; Lu, Di; Lv, Zhen; Zhuang, Runzhou; Liu, Zhikun; Wei, Xuyong; Zhou, Lin; Xu, Xiao*; Zheng, Shusen.Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.Translational Research, 2016, 168: 107-121.
[86]Xie, Haiyang; Xu, Xiao; Chen, Jianmei; Li, Lingling; Wang, Jianguo; Fang, Tao; Zhou, Lin; Wang, Hangxiang*; Zheng, Shusen.Rational design of multifunctional small-molecule prodrugs for simultaneous suppression of cancer cell growth and metastasis in vitro and in vivo.Chemical Communications, 2016, 52(32): 5601-5604.
[87]Xu Xiao; Lu Di; Ling Qi; Wei Xuyong; Wu Jian; Zhou Lin; Yan Sheng; Wu Liming; Geng Lei; Ke Qinghong; Gao Feng; Tu Zhenhua; Wang Weilin; Zhang Mangli; Shen Yan; Xie Haiyang; Jiang Wenshi; Wang Haibo; Zheng Shusen*. Liver transplantation for hepatocellular carcinoma beyond the Milan Criteria, Gut. 2016; 65(6):1035-1041. (IF=19.819)
[88]Wang, Jianguo; Wang, Hangxiang*; Li, Jie; Liu, Zhikun; Xie, Haiyang; Wei, Xuyong; Lu, Di; Zhuang, Runzhou; Xu, Xiao*; Zheng, Shusen*. iRGD-Decorated Polymeric Nanoparticles for the Efficient Delivery of Vandetanib to Hepatocellular Carcinoma: Preparation and in Vitro and in Vivo Evaluation. ACS Applied Materials & Interfaces, 2016, 8(30): 19228-19237. (IF=8.758)
[89]Xu, Xiao; Ling, Qi; Wang, Jianguo; Xie, Haiyang; Wei, Xuyong; Lu, Di; Hu, Qichao; Zhang, Xuanyu; Wu, Liming; Zhou, Lin; Zheng, Shusen*. Donor miR-196a-2 polymorphism is associated with hepatocellular carcinoma recurrence after liver transplantation in a Han Chinese population. International Journal of Cancer, 2016, 138(3): 620-629. (IF=5.145)
[90]Wang Hangxiang; Xie Haiyang; Wang Jianguo; Wu Jiaping; Ma Xueji; Li Lingling; Wei Xuyong; Ling Qi; Song Penghong; Zhou Lin; Xu Xiao*; Zheng Shusen*. Self-Assembling Prodrugs by Precise Programming of Molecular Structures that Contribute Distinct Stability, Pharmacokinetics, and Antitumor Efficacy. Advanced Functional Materials, 2015, 25(31): 4956-4965. (IF=16.836)
[91]Xu Xiao#; Liu Zhikun#; Zhou Lin; Xie Haiyang; Cheng Jun; Ling Qi; Wang Jianguo; Guo Haijun; Wei Xuyong; Zheng Shusen*. Characterization of genome-wide TFCP2 targets in hepatocellular carcinoma: implication of targets FN1 and TJP1 in metastasis. Journal of Experimental & Clinical Cancer Research. 2015; 34(1):6. (IF=7.068)
[92]Wei Xuyong; Li Jie; Xie Haiyang; Wang Hangxiang; Wang Jianguo; Zhang Xuanyu; Zhuang Runzhou; Lu Di; Ling Qi; Zhou Lin; Xu Xiao*; Zheng Shusen*. Chloride intracellular channel 1 participates in migration and invasion of hepatocellular carcinoma by targeting maspin ,Journal of Gastroenterology and Hepatology,2015,30(1):208-216
[93]Wang Lijun; Wang Jianguo; Zhang Xuanyu; Li Jie; Wei Xuyong; Cheng Jun; Ling Qi; Xie Haiyang; Zhou Lin; Xu Xiao*; Zheng Shusen*.Diagnostic Value of Preoperative Needle Biopsy for Tumor Grading Assessment in HepatocellularCarcinoma.PLoS One, 2015, 10(12).
[94]Ding Songming; Chen Guoliang; Zhang Wu; Xing Chunyang; Xu Xiao; Xie Haiyang; Lu Aili; Chen Kangjie; Guo Haijun; Ren Zhigang; Zheng Shusen; Zhou Lin*.MRC-5fibroblast-conditioned medium influences multiple pathways regulating invasion,migration, proliferation, and apoptosis in hepatocellular carcinoma.Journal of Translational Medicine, 2015, 13(237).
[95]Xiao Min#; Xu Xiao#; Zhu Hengkai; Zhuang Runzhou; Xiang Penghui; Wang Ting; Zhuang Li; Wei Qiang; Wei Xuyong; Zhang, Lin; Wu Jian; Zheng Shusen*.Efficacy and safety of basiliximab in livertransplantation for patients with hepatitis B virus-related diseases: a singlecentre study.International Journal of Clinical Practice, 2015, 69(特刊): 35-42.
[96]Xia, Weiliang; Ke, Qinghong; Wang, Ye; Wang, Weilin; Zhang, Min; Shen, Yan; Wu, Jian; Xu, Xiao; Zheng, Shusen*.Predictive value of pre-transplant platelet to lymphocyte ratio for hepatocellular carcinoma recurrence after liver transplantation.World Journal of Surgical Oncology, 2015, 13: 60.
[97]Wang, Li-Ying; Zheng, Shu-Sen*; Xu, Xiao; Wang, Wei-Lin; Wu, Jian; Zhang, Min; Shen, Yan; Yan, Sheng; Xie, Hai-Yang; Chen, Xin-Hua; Jiang, Tian-An; Chen, Fen.A score model for predicting post-liver transplantation survival in HBV cirrhosis-related hepatocellular carcinoma recipients: a single center 5-year experience.Hepatobiliary and Pancreatic Diseases International, 2015, 14(1): 43-49.
[98]Xie, Haiyang; Xing, Chunyang; Cao, Guoqiang; Wei, Bajin; Xu, Xiao; Song, Penghong; Chen, Leiming; Chen, Hai; Yin, Shengyong; Zhou, Lin; Zheng, Shusen*.Association of RNF43 with cell cycle proteins involved in p53 pathway.International Journal of Clinical and Experimental Pathology, 2015, 8(11): 14995-15000.
[99]Ling Qi; Xu Xiao*; Wang Kai; Wang Chao; Xiang Penghui; Zhang Xuanyu; Zhuang Runzhou; Xie Haiyang; Zheng Shusen*.Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study.Medicine, 2015, 94(35).
[100]Xia Weiliang; Ke Qinghong; Wang Ye; Feng Xiaowen; Guo Haijun; Wang Weilin; Zhang Min; Shen Yan; Wu Jian; Xu Xiao; Yan Sheng; Zheng Shusen*.Donation after cardiacdeath liver transplantation: Graft quality evaluation based on pretransplantliver biopsy.Liver Transplantation, 2015, 21(6): 838-846.
[101]Xie Haiyang; Xing Chunyang; Wei Bajin; Xu Xiao; Wu Liming; Wu Jian; Chen Leiming; Cao Guoqiang; Chen Hai; Meng Xueqin; Yin Shengyong; Zhou Lin; Zheng Shusen*.Polymorphisms of FGFR1 in HBV-related hepatocellularcarcinoma.Tumor Biology, 2015, 36(11): 8881-8886.
[102]Wang Hangxiang; Xie Haiyang; Wu Jiaping; Wei Xuyong; Zhou Lin; Xu Xiao*; Zheng Shusen*. Structure-Based Rational Design of Prodrugs to Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy. Angewandte Chemie International Edition, 2014, 53(43): 11532-11537. (IF=12.959)
[103]Wei Xuyong; Li Jie; Xie Haiyang; Ling Qi; Wang Jianguo; Lu Di; Zhou Lin; Xu Xiao*; Zheng Shusen*. Proteomics-based identification of the tumor suppressor role of aminoacylase 1 in hepatocellular carcinoma. Cancer Letters, 2014; 351(1): 117-125. (IF=7.36)
[104]Wang Hangxiang; Chen Wei; Xie Haiyang; Wei Xuyong; Yin Shengyong; Zhou Lin; Xu Xiao*; Zheng Shusen*. Biocompatible, chimeric peptide-condensed supramolecular nanoparticles for tumor cell-specific siRNA delivery and gene silencing. Chemical Communications. 2014; 50(58): 7806-7809. (IF=5.996)
[105]Chen Jun#; Xu Xiao#; Wu Jian; Ling Qi; Wang Kai; Wang Weilin; Zhang Min; Shen Yan; Zhou Lin; Xie Haiyang; Zheng Shusen*.The Stratifying Value of Hangzhou Criteria in Liver Transplantation for Hepatocellular Carcinoma.PLos One, 2014, 9(3): e93128.
[106]Lu Di#; Xu Xiao#; Wang Jianguo; Ling Qi; Xie Haiyang; Zhou Lin; Yan Sheng; Wang Weilin; Mang Min; Shen Yan; Zheng Shusen*.The influence of a contemporaneous portal and hepatic artery revascularization protocol on biliary complications after liver transplantation,Surgery,2014,155(1):190-195
[107]Xu Xiao#; Guo Haijun#; Xie Haiyang; Li Jie; Zhuang Runzhou; Ling Qi; Zhou Lin; Wei Xuyong; Liu Zhikun; Ding Songming; Chen Kangjie; Xu Zhiyuan; Zheng Shusen*. ZIP4, a Novel Determinant of Tumor Invasion in Hepatocellular Carcinoma, Contributes to Tumor Recurrence after Liver Transplantation ,International Journal of Biological Sciences,2014,10(3):245-256
[108]Lu, Di*; Xu, Xiao; Zheng, Shusen.Reply to: "The influence of contemporaneous revascularization on binary complications after liver transplantation".Surgery, 2014, 156(3): 739-740.
[109]Xie Haiyang; Xing Chunyang; Wei Bajin; Xu Xiao; Wu Jian; Chen Leiming; Cao Guoqiang; Chen Hong; Chen Kangjie; Yin Shengyong; Wu Liming; Zhou Lin; Zheng Shusen*.Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma.Tissue Antigens, 2014, 84(3): 264-270.
[110]Gao Feng; Xu Xiao; Zhu Yangbo; Wei Qiang; Zhou Bin; Shen Xiaoyong; Ling Qi; Xie Haiyang; Wu Jian; Wang Weilin; Zheng Shusen*.Impact of intra-operative cholangiography and parenchymal resection to donor liver function in living donor liver transplantation.Hepatobiliary and Pancreatic Diseases International, 2014, 13(3): 259-263.
[111]Yu Xiaobo; Wei Bajin; Dai Yifan; Zhang Min; Wu Jian; Xu Xiao; Jiang Guoping; Zheng Shusen; Zhou Lin*.Genetic Polymorphism of Interferon Regulatory Factor 5 (IRF5) Correlates with Allograft Acute Rejection of Liver Transplantation.PLos One, 2014, 9(4): e94426.
[112]Ling Qi; Xie Haiyang; Lu Di; Wei Xuyong; Gao Feng; Zhou Lin; Xu Xiao*; Zheng Shusen*. Association between donor and recipient TCF7L2 gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation in a Han Chinese population. Journal of Hepatology, 2013; 58(2): 271-7. (IF=20.582)
[113]Shen, Xiaoyong; Lu, Di; Xu, Xiao; Wang, Jianguo; Wu, Jian; Yan, Sheng; Zheng, Shu-sen*.A novel distinguishing system for the diagnosis of malignant pancreatic cystic neoplasm.European Journal of Radiology, 2013, 82(11).
[114]Ling Qi; Xu Xiao; Zheng Shusen; Kalthoff Holger*.The diversity between pancreatic head and body/tail cancers: clinical parameters and in vitro models.Hepatobiliary and Pancreatic Diseases International, 2013, 12(5): 480-487.
[115]Wei Qiang; Xu Xiao; Ling Qi; Zheng Shusen*.Indefinite antiviral therapy may be required after surgical resection for hepatocellular carcinoma complicating chronic hepatitis B.Journal of Research in Medical Sciences, 2013, 18(8): 726-730.
[116]Liu, Zhikun; Ling, Qi; Wang, Jianguo; Xie, Haiyang; Xu, Xiao; Zheng, Shusen*.Annexin A2 is not a good biomarker for hepatocellular carcinoma in cirrhosis.ONCOLOGY LETTERS, 2013, 6(1): 125-129.
[117]Wei Qiang; Xu Xiao; Ling Qi; Zhou Bo; Zheng Shusen*.Perioperative antiviral therapy for chronic hepatitis B-related hepatocellular carcinoma.Hepatobiliary and Pancreatic Diseases International, 2013, 12(3): 251-255.
[118]Ling Qi; Dong Fengqin; Geng Lei; Liu Zhikun; Xie Haiyang; Xu Xiao*; Zheng Shusen*.Impacts of TCF7L2 gene polymorphisms on the susceptibility of hepatogenous diabetes and hepatocellular carcinoma in cirrhotic patients.Gene, 2013, 522(2): 214-218.
[119]Ling, Qi; Xu, Xiao; Dong, Fengqin; Zheng, Shusen*.Reply to: "New onset diabetes after transplantation: A type 1.5 diabetes or latent autoimmune diabetes of adults?".JOURNAL OF HEPATOLOGY, 2013, 58(5): 1060-1061.
[120]Xu Xiao; Liu Xiaoli; Ling Qi; Wei Qiang; Liu Zhikun; Xu Xiaowei; Zhou Lin; Zhang Min; Wu Jian; Huang Jianrong; Sheng Jifang; Zheng Shusen*; Li Lanjuan*.Artificial Liver Support System Combined with Liver Transplantation in the Treatment of Patients with Acute-on-Chronic Liver Failure.PLos One, 2013, 8(3): e58738.
[121]Wu Liming; Zhou Lin; Xu Jun; Wei Bajin; Cheng Jun; Xu Xiao; Xi Bin; Xie Haiyang; Zheng Shusen*.Lack of association between genetic polymorphisms in cytokine genes and tumor recurrence in patients with hepatocellular carcinoma undergoing transplantation.Hepatobiliary and Pancreatic Diseases International, 2013, 12(1): 54-59.
[122]Xu, Xiao; Wang, Jianguo; Liu, Zhikun; Wei, Xuyong; Zhuang, Runzhou; Lu, Di; Zhou, Lin; Xie, Haiyang; Zheng, Shusen*.LEPREL1 Expression in Human Hepatocellular Carcinoma and Its Suppressor Role on Cell Proliferation.Gastroenterology Research and Practice, 2013, 86(7): 109759.
[123]Ling Qi; Wang Kai; Lu Di; Guo Haijun; Jiang Wenshi; He Xiangxiang; Xu Xiao; Zheng Shusen*.Major influence of renal function on hyperlipidemia after living donor liver transplantation.World Journal of Gastroenterology, 2012, 18(47): 7033-7039.
[124]Jin Liming; Jin Shuifang; Liu Yuanxing; Zhou Lin; Xie Haiyang; Yan Sheng; Xu Xiao; Zheng Shusen*.Ischemic preconditioning enhances hepatocyte proliferation in the early phase after ischemia under hemi-hepatectomy in rats.Hepatobiliary and Pancreatic Diseases International, 2012, 11(5): 521-526.
[125]Guo Hua; Shen Yan; Wang Weilin; Zhang Min; Li Hong; Wu Yingsheng; Yan Sheng; Xu Xiao; Wu Jian; Zheng Shusen*.Castleman disease mimicked pancreatic carcinoma: report of two cases.World Journal of Surgical Oncology, 2012, 10: 154.
[126]Xu Xiao#; Wei Xuyong#; Ling Qi; Wang Kai; Bao Haiwei; Xie Haiyang; Zhou Lin; Zheng Shusen*.Inaccurate preoperative imaging assessment on biliary anatomy not increases biliary complications after living donor liver transplantation.European Journal of Radiology, 2012, 81(4).
[127]Ling Qi#; Xu Xiao#; Wei Qiang; Liu Xiaoli; Guo Haijun; Zhuang Li; Chen Jiajia; Xia Qi; Xie Haiyang; Wu Jian; Zheng Shusen*; Li Lanjuan.Downgrading MELD Improves the Outcomes after Liver Transplantation in Patients with Acute-on-Chronic Hepatitis B Liver Failure.PLos One, 2012, 7(1): e30322.
[128]Xu Xiao#; Wei Xuyong#; Ling Qi; Cheng Jun; Zhou Bin; Xie Haiyang; Zhou Lin; Zheng Shusen*.Identification of two portal vein tumor thrombosis associated proteins in hepatocellular carcinoma: Protein disulfide-isomerase A6 and apolipoprotein A-I.Journal of Gastroenterology and Hepatology, 2011, 26(12): 1787-1794.
[129]Cheng Jun; Xie Haiyang; Xu Xiao; Wu Jian; Wei Xuyong; Su Rong; Zhang Wu; Lv Zhen; Zheng Shusen*; Zhou Lin.NDRG1 as a biomarker for metastasis, recurrence and of poor prognosis in hepatocellular carcinoma.Cancer Letters, 2011, 310(1): 35-45.
[130]Xu Xiao; Tu Zhenhua; Wang Bei; Ling Qi; Zhang Lin; Zhou Lin; Jiang Guoping; Wu Jian; Zheng Shusen*.A novel model for evaluating the risk of hepatitis B recurrence after liver transplantation.Liver International, 2011, 31(10): 1477-1484.
[131]Xu Xiao; Ling Qi; Wei Qiang; Wang Kai; Zhou Bin; Zhuang Li; Zhou Lin; Zheng Shusen*.Korean Red Ginseng: A New Approach for the Treatment of Graft-Versus-Host Disease after Liver Transplantation.Transplantation Proceedings, 2011, 43(7): 2651-2655.
[132]Ling Qi; Xu Xiao; Wei Xuyong; Wang Weibing; Zhou Bin; Wang Bei; Zheng Shusen*.Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome C.Journal of Experimental & Clinical Cancer Research, 2011, 30: 66.
[133]Zhang Wu; Zhou Lin; Ding Songming; Xie Haiyang; Xu Xiao; Wu Jian; Chen Qixin; Zhang Feng; Wei Bajin; Eldin Ahmed Taki; Zheng Shusen*.Aberrant methylation of the CADM1 promoter is associated with poor prognosis in hepatocellular carcinoma treated with liver transplantation.Oncology Reports, 2011, 25(4): 1053-1062.
[134]Ling Qi; Xu Xiao; Wei Qiang; Wei Xuyong; Wang Zhuoyi; Zhou Lin; Zheng Shusen*.Impact of Preexisting Diabetes Mellitus on Outcome After Liver Transplantation in Patients with Hepatitis B Virus-Related Liver Disease.Digestive Diseases and Sciences, 2011, 56(3): 889-893.
[135]Xu Xiao; Wei Qiang; Wang Kai; Ling Qi; Xie Haiyang; Zhou Lin; Zheng Shusen*.Anticancer Effects of Huaier are Associated with Down-Regulation of P53.Asian Pacific Journal of Cancer Prevention, 2011, 12(9): 2251-2254.
[136]Feng Zhiying; Xu Xiao; Wu Lingjiao; Wu Jian; Zhu Shengmei; Zheng Shusen*.Downregulation of endothelin-1 by somatostatin improves liver function of recipients undergoing adult-to-adult living donor liver transplantation.Chinese Medical Journal, 2010, 123(15): 1961-1966.
[137]Feng Zhiying; Xu Xiao; Zhu Shengmei; Bein Berthold; Zheng Shusen*.Effects of Low Central Venous Pressure During Preanhepatic Phase on Blood Loss and Liver and Renal Function in Liver Transplantation.World Journal of Surgery, 2010, 34(8): 1864-1873.
[138]Xu Xiao; Ling Qi; Wei Qiang; Wu Jian; Gao Feng; He Zenglei; Zhou Lin; Zheng Shusen*.An effective model for predicting acute kidney injury after liver transplantation.Hepatobiliary and Pancreatic Diseases International, 2010, 9(3): 259-263.
[139]Zhao, Hong; Hu, Jian-Hua; Zhou, Lin; Xu, Xiao; Wu, Jian; Meng, Xue-Qin; Fan, Jun; Ma, Wei-Hang.Impact of human leukocyte antigen matching on hepatitis B virus recurrence after liver transplantation.HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 2010, 9(2): 139-143.
[140]Cheng Jun; Zhou Lin; Xie Qinfen; Xie Haiyang; Wei Xuyong; Gao Feng; Xing Chunyang; Xu Xiao; Li Lanjuan; Zheng Shusen*.The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells.Proteomics, 2010, 10(8): 1557-1572.
[141]Yan Sheng; Zhang Qiyi; Yu Yusheng; He Jiangjuan; Wang Weilin; Zhang Min; Shen Yan; Wu Jian; Xu Xiao; Zheng Shusen*.Microsurgical reconstruction of hepatic artery in living donor liver transplantation: experiences and lessons.Hepatobiliary and Pancreatic Diseases International, 2009, 8(6): 575-580.
[142]Chen Haiyong; Wang Weilin; Xie Haiyang; Xu Xiao; Wu Jian; Jiang Zhijun; Zhang Mangli; Zhou Lin; Zheng Shusen*.A pathogenic role of IL-17 at the early stage of corneal allograft rejection.Transplant Immunology, 2009, 21(3): 155-161.
[143]Xu, Xiao; Ling, Qi; Zhang, Min; Gao, Feng; He, Zenglei; You, Jingya; Zheng, Shusen.Outcome of Patients With Hepatorenal Syndrome Type 1 After Liver Transplantation: Hangzhou Experience.TRANSPLANTATION, 2009, 87(10): 1514-1519.
[144]Ji Haofeng; Wang Weilin; Shen Yan; Zhang Min; Liang Tingbo; Wu Jian; Xu Xiao; Yan Sheng; Zheng Shusen*.Reduced-size liver transplantation for glycogen storage disease.Hepatobiliary and Pancreatic Diseases International, 2009, 8(1): 106-108.
[145]Gao Feng; Xu Xiao; Ling Qi; Wu Jian; Zhou Lin; Xie Haiyang; Wang Huiping; Zheng Shusen*.Efficacy and safety of moderately steatotic donor liver in transplantation.Hepatobiliary and Pancreatic Diseases International, 2009, 8(1): 29-33.
[146]Xu xiao; Ke Qinghong; Shao Zhexin; Wu Jian; Chen Jun; Zhou Lin; Zheng Shusen*.The Value of Serum alpha-Fetoprotein in Predicting Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma.Digestive Diseases and Sciences, 2009, 54(2): 385-388.
[147]Xu Xiao; Ling Qi; Gao Feng; He Zenglei; Xie Haiyang; Zheng Shusen*.Hepatoprotective Effects of Marine and Kuhuang in Liver Transplant Recipients.American Journal of Chinese Medicine, 2009, 37(1): 27-34.
[148]Xu Xiao; Ling Qi; He Zenglei; Gao Feng; Zheng Shusen*.Post-transplant diabetes mellitus in liver transplantation: Hangzhou experience.Hepatobiliary and Pancreatic Diseases International, 2008, 7(5): 465-470.
[149]Wu, Jian; Wang, Weilin; Zhang, Min; Shen, Yan; Liang, Tingbo; Yu, Pengfei; Xu, Xiao; Yan, Sheng; Zheng, Shusen.Reconstruction of middle hepatic vein in living donor liver transplantation with modified right lobe graft: a single center experience.TRANSPLANT INTERNATIONAL, 2008, 21(9): 843-849.
[150]Jiang Zhijun; Liang Tingbo; Feng Xiaoning; Wang Weilin; Shen Yan; Zhang Min; Wu Jian; Xu Xiao; Zheng Shusen*.Arcuate ligament syndrome inducing hepatic artery thrombosis after liver transplantation.Hepatobiliary and Pancreatic Diseases International, 2008, 7(4): 433-436.
[151]Zheng Shusen*; Xu Xiao; Wu Jian; Chen Jun; Wang Weilin; Zhang Min; Liang Tingbo; Wu Liming.Liver transplantation for hepatocellular carcinoma: Hangzhou experiences.Transplantation, 2008, 85(12): 1726-1732.
[152]Wu Jian; Xu Xiao; Liang Tingbo; Wang Weilin; Zhang Min; Shen Yan; Ling Qi; Tu Zhenhua; Lu Anwei; Zheng Shusen*.Long-term outcome of combined liver-kidney transplantation: a single-center experience in China.Hepato-Gastroenterology, 2008, 55(82-83): 334-337.
[153]Ling, Gi; Xu, Xiao; Li, Junjian; Wu, Jian; Chen, Jie; Xie, Haiyang; Zheng, Shusen.A new serum cystatin C-based equation for assessing glomerular filtration rate in liver transplantation.CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2008, 46(3): 405-410.
[154]Chen Jun; Xu Xiao; Ling Qi; Wu Jian; Zheng Shu-sen*.Role of Pittsburgh Modified TNM Criteria in prognosis prediction of liver transplantation for hepatocellular carcinoma.Chinese Medical Journal, 2007, 120(24): 2200-2203.
[155]Ling Q, Xu X, Li JJ, Chen J, Shen JW, Zheng SS. Alternative definition of acute kidney injury following liver transplantation: based on serum creatinine and cystatin C levels. Transplant Proc. 2007;39(10):3257-3260.
[156]Xu Xiao; Ling Qi; Wu Jian; Chen Jun; Gao Feng; Feng Xiaoning; Zheng Shusen*.A novel prognostic model based on serum levels of total bilirubin and creatinine early after liver transplantation.Liver International, 2007, 27(6): 816-824.
[157]Li Xiaodong; Wu Liming; Xie Haiyang; Xu Xiao; Zhou Lin; Liang Tingbo; Wang Weilin; Shen Yan; Zhang Min; Zheng Shusen*.No association exists between E-cadherin gene polymorphism and tumor recurrence in patients with hepatocellular carcinoma after transplantation.Hepatobiliary and Pancreatic Diseases International, 2007, 6(3): 254-258.
[158]Xu Xiao; Man Kwan; Zheng Shusen; Liang Tingbo; Lee Terence K; Ng Kevin T; Fan Sheung Tat; Lo Chung Mau*.Attenuation of acute phase shear stress by somatostatin improves small-for-size liver graft survival.Liver Transplantation, 2006, 12(4): 621-627.
[159]Xu, Shengjun; Ling, Sunbin; Shan, Qiaonan; Ye, Qianwei; Zhan, Qifan; Jiang, Guangjiang; Zhuo, Jianyong; Pan, Binhua; Wen, Xue; Feng, Tingting; Lu, Haohao; Wei, Xuyong; Xie, Haiyang; Zheng, Shusen; Xiang, Jiajia*; Shen, Youqing; Xu, Xiao*.Self-Activated Cascade-Responsive Sorafenib and USP22 shRNA Co-Delivery System for Synergetic Hepatocellular Carcinoma Therapy.Advanced Science, 2003042.
[160]Zhang, Zhensheng; Xu, Li; Xu, Xiao*.The role of transcription factor 7-like 2 in metabolic disorders.Obesity Reviews.
[161]Yu, Jiongjie; Liu, Zhikun; Li, Changbiao; Wei, Qiang; Zheng, Shusen; Saeb-Parsy, Kourosh*; Xu, Xiao*.Regulatory T Cell Therapy Following Liver Transplantation.Liver Transplantation.
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[63]張宇, 徐驍, 彭志毅, 王偉林, 張珉, 吳健, 俞軍, 鄭樹森. 成人活體右半肝移植術(shù)前供肝體積評估100例資料分析[J]. 中華移植雜志(電子版), 2010, 4 (01): 17-19.
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[65]陳耀敏, 鄭樹森, 王偉林, 張珉, 沈巖, 吳健, 嚴盛, 徐驍. 拉米夫定聯(lián)合乙型肝炎免疫球蛋白防治肝移植術(shù)后乙型肝炎復(fù)發(fā)的療效研究[J]. 浙江醫(yī)學(xué), 2008, (09): 989-990.
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[67]張啟逸, 徐驍, 鄭樹森. 再次肝移殖的適應(yīng)證和預(yù)后[J]. 中華普通外科雜志, 2006, (11): 838-840.
[68]胡振華, 徐驍, 梁廷波, 鄭樹森. 胰腺實性-假乳頭狀瘤的臨床診治[J]. 中華普通外科雜志, 2006, (09): 679-680.
[69]吳健, 鄭樹森, 吳麗花, 蔣國平, 徐驍. 氟伐他汀抑制內(nèi)皮細胞MHCⅡ表達的研究[J]. 中華微生物學(xué)和免疫學(xué)雜志, 2006, (06): 489-493.
[70]邵浙新, 徐驍, 鄭樹森, 梁廷波, 柯慶宏, 馬怡平. 肝細胞癌患者肝移植術(shù)后甲胎蛋白的變化與腫瘤復(fù)發(fā)[J]. 中華普通外科雜志, 2006, (05): 351-353.
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[75]黃東勝,徐驍,鄭樹森,陳建峰. NS398通過環(huán)氧合酶-2非依賴途徑誘導(dǎo)胰腺癌BxPC-3細胞凋亡[J]. 中國醫(yī)學(xué)科學(xué)院學(xué)報, 2005, (05): 601-605.
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[77]鄭樹森,徐驍,梁廷波,夏偉良,王偉林,吳健,陳海勇. 原位肝移植術(shù)后膽道并發(fā)癥治療經(jīng)驗[J]. 中華普通外科雜志, 2005, (08): 467-469.
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[85]鄭樹森,徐驍,李蘭娟,梁廷波,高峰,王偉林,沈巖,楊芊. 人工肝支持系統(tǒng)聯(lián)合肝移植治療晚期重型肝炎的臨床經(jīng)驗[J]. 中華普通外科雜志, 2004, (09): 4-6.
[86]徐驍. 重視圍手術(shù)期處理,提高肝移植技術(shù)水平[J]. 中華醫(yī)學(xué)信息導(dǎo)報, 2004, (15): 12-13.
[87]謝海洋,徐驍,鄭樹森,梁廷波,黃東勝. NS-398對肝癌細胞HepG2增殖和凋亡的影響[J]. 中國病理生理雜志, 2004, (07): 96-100.
[88]葉明,徐驍,沈巖,鄭樹森. 胰高血糖素瘤綜合征的診治[J]. 浙江醫(yī)學(xué), 2004, (06): 64-66.
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[101]鄭樹森,梁廷波,徐驍,王偉林,沈巖,張珉,黃東勝. 肝臟移植10年120例經(jīng)驗回顧[J]. 中華普通外科雜志, 2003, (02): 6-8.
[102]葉靜,徐驍,鄭樹森. 胰腺癌的輔助治療[J]. 浙江醫(yī)學(xué), 2003, (01): 65-67.
[103]徐驍,詹麗杏,黃東勝,呂賓,梁廷波,鄭樹森. 胰島素瘤62例診治體會[J]. 胰腺病學(xué), 2002, (03): 133-135.
[104]黃東勝,鄭樹森,徐驍,王偉林,梁廷波,沈巖,張珉,盧安衛(wèi),吳健,章愛斌. 肝移植術(shù)后免疫抑制劑的替換應(yīng)用[J]. 中華器官移植雜志, 2002, (04): 6-8.
[105]鄭樹森,黃東勝,吳健,王偉林,沈巖,張珉,沈倩云,盧安衛(wèi),傅佩芬,徐驍. 不采用體外靜脈-靜脈轉(zhuǎn)流技術(shù)的經(jīng)典原位肝移植術(shù)[J]. 中華外科雜志, 2002, (05): 9-11.
[106]鄭樹森,吳健,黃東勝,王偉林,梁廷波,沈巖,張珉,徐驍. 肝臟移植在治療肝臟惡性腫瘤中的作用[J]. 中華肝膽外科雜志, 2002, (05): 10-12.
[107]黃東勝,徐驍,鄭樹森,梁廷波,張珉,王偉林,沈巖,沈倩云,吳健,吳應(yīng)盛. 人體原位肝臟移植術(shù)后膽道與血管并發(fā)癥的放射介入治療[J]. 中華肝膽外科雜志, 2002, (05): 24-27.
[108]鄭樹森,徐驍,吳健,梁廷波,黃東勝,王偉林,張珉,沈巖. 原位肝移植后膽道并發(fā)癥的診斷與治療[J]. 中華器官移植雜志, 2002, (03): 26-28.
[109]鄭樹森,黃東勝,王偉林,梁廷波,張珉,沈巖,吳健,徐驍,盧安衛(wèi),廖勝洋. 71例人體原位肝移植對終末期肝病的治療[J]. 中華肝臟病雜志, 2002, (01): 7-9.
[110]鄭樹森,李啟勇,徐驍,黃東勝,梁廷波,吳鍵,朱偉芳. 192例胰腺癌的外科治療及隨訪[J]. 浙江醫(yī)學(xué), 2002, (01): 4-6.
[111]鄭樹森,李蘭娟,黃東勝,王偉林,徐驍,吳健,徐曉微,楊芊,陳月美. 人工肝臟支持系統(tǒng)在肝臟移植圍手術(shù)期的應(yīng)用[J]. 中國實用外科雜志, 2002, (01): 50-52.
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[113]徐驍, 鄭樹森, 梁廷波, 吳健, 黃東勝. 胰管結(jié)石的診斷和治療[J]. 中華肝膽外科雜志, 2001, (09): 548.
[114]吳健, 鄭樹森, 徐驍, 梁廷波, 黃東勝. 選擇性術(shù)中膽道造影的臨床應(yīng)用價值[J]. 中華肝膽外科雜志, 2001, (07): 406-408.
[115]鄭樹森,粱廷波,黃東勝,俞軍,徐驍,朱偉芳. 胰腺癌147例的診斷治療分析[J]. 中華普通外科雜志, 2000, (05): 13-16.
[116]徐驍,鄭樹森,陳智,吳靈嬌,梁庭波,黃東勝. nm23-H_1基因mRNA在人肝細胞癌中的表達[J]. 中華肝膽外科雜志, 1999, (06): 39-41.
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[119]鄭樹森,梁廷波,于吉人,黃東勝,徐驍. 急性胰腺炎個體化綜合治療68例[J]. 浙江醫(yī)科大學(xué)學(xué)報, 1999, (02): 22-24.
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會議論文:
[1]Wang, J.; Xu, S.; Tao, Y.; Xu, X.; Zheng, S.Salinomycin-loaded LA-SN38 nanoprodrugs incorporated into DSPE-PEG2000 micelles enhanced anticancer activity by inhibiting cancer stem cell in liver cancer.25th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2019-05-15 To 2019-05-18.
[2]Xu, L.; Wang, H.; Zheng, S.; Xu, X..PLK1 inhibitor synergizes SN38 prodrug-based nanoparticles to treat hepatocellular carcinoma.25th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2019-05-15 To 2019-05-18.
[3]Al-ameri, A.; Shao, Z.; Zhang, X.; Guo, H.; Ke, Q.; Liu, P.; Liu, Z.; Wei, X.; Xie, H.; Zhou, L.; Zheng, S.; Xu, X.Preoperative risk stratification for recurrence of negative-AFP hepatocellular carcinoma after liver transplanation.25th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2019-05-15 To 2019-05-18.
[4]Yang, F.; Yang, P.; Yang, M.; Zhuo, J.; Wang, J.; Lu, D.; Zheng, S.; Niu, T.; Xu, X.Non-invasive diagnosis model for pancreatic cystic tumors based on machine learning-radiomics using contrast-enhanced CT.25th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2019-05-15 To 2019-05-18.
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[9]Guo Haijun; Xu Xiao; Ke Qinghong; Wei Qiang; Wei Xuyong; Yang Zhe; Shen Yan; Wu Jian; Yan Sheng; Zhang Min; Zheng Shusen.Efficacy of Middle Hepatic Vein Reconstruction in Adult Right-Lobe Living Donor Liver Transplantation: A Single Center Experience.22nd Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2016-05-04 to 2016-05-07.
[10]Xu Xiao; Ling Qi; Wei Xuyong; Zhuang Runzhou; Wei Qiang; Wu Jian; Xie Haiyang; Zhou Lin; Zheng Shusen.Genetic Susceptibility To Hepatocellular Carcinoma in Han Chinese Population.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[11]Wang Kai; Xu Xiao; Xie Haiyang; Zhou Lin; Ling Qi; Xiang Penghui; Zhu Hengkai; Feng Xiaowen; Liu Jimin; Zheng Shusen.Does Neutrophil To Lymphocyte Ratio Predict Acute Rejection and Survival in Liver Transplantation?21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 To 2015-07-11.
[12]Lu Di; Xu Xiao; Zheng Shusen.The Prognostic Capacity of Micro-Vascular Invasion in Liver Transplantation for Small Hepatocellular Carcinoma.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 To 2015-07-11.
[13]Zhang Xuanyu; Xu Xiao; Zhou Ling; Xie Haiyang; Zheng Shusen.A Novel Gene HAUS3 Acts as a Tumor Promoter in Hepatocellular Carcinoma.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 To 2015-07-11.
[14]Zhuang Li; Tu Zhenhua; Zhang Min; Xu Xiao; Zheng Shusen.Analysis of Long-Term Outcome of Combined Liver and Kidney Transplantation for 26 Patients.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 To 2015-07-11.
[15]Ling Qi; Xu Xiao; Wang Kai; Xiang Penghui; Zhang Xuanyu; Zhuang Runzhou; Zhuang Li; Zheng Shusen.Tacrolimus Might Cause Hepatogenous Diabetes After Liver Transplantation.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 To 2015-07-11.
[16]Wang Ting; Xu Xiao; Wei Xu Yong; Wang Kai; Xiao Min; Zhu Heng Kai; Xie Hai Yang; Zheng Shu Sen.SERPINB1 and FTL: Two Proteins Associated With Hepatocellular Carcinoma.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[17]Wei Xuyong; Xu Xiao; Zhang Runzhou; Zhou Lin; Xie Haiyang; Wang Jianguo; Zhang Xuanyu; Zheng Shusen.The Distinct Proteomic Profiling of Hepatocellular Carcinoma Based on alpha-Fetoprotein Expression.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[18]Wang Jianguo; Wang Hangxiang; Xie Haiyang; Wei Xuyong; Xu Xiao; Zheng Shusen.Nanoparticle-Based Mediated Vandetanib Efficiently Suppress Tumor Growth In Vivo.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[19]Xiao Min; Xu Xiao; Zhu Hengkai; Zhuang Runzhou; Wang Ting; Wei Xuyong; Wu Jian; Zheng Shuseng.Efficacy and Safety of Basiliximab in Liver Transplantation for Patients With Hepatitis B Virus-Related Diseases: A Single Center Study.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[20]Wang Chao; Xu Xiao; Lu Di; Wei Xuyong; Zhuang Runzhou; Zhou Lin; Zheng Shusen.Single Nucleotide Polymorphism of MTHFR Predict the Recurrence of Hepatocellular Carcinoma After Liver Transplantation in Hepatocellular Carcinoma Patients.21st Annual International Congress of the International-Liver-Transplant-Society (ILTS), 2015-07-08 to 2015-07-11.
[21]吳李鳴,楊喆,謝海洋,徐驍,王偉林,張峰... & 鄭樹森. (2015). 新型長鏈非編碼RNA HOTTIP對肝癌肝移植受者腫瘤復(fù)發(fā)風(fēng)險的評估價值. (eds.) 2015浙江省腫瘤外科學(xué)術(shù)年會暨首屆錢江國際腫瘤外科高峰論壇論文匯編 (pp.90).
[22]Wei Qiang; Xu Xiao; Zhu Yangbo; Ling Qi; Ke Qinghong; Wang Weiling; Zheng Shusen.Family History May Not Influences the Early Onset of Hepatocellular Carcinoma.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 To 2014-06-07.
[23]Yu, Xiaobo; Wei, Bajin; Zhang, Min; Wu, Jian; Xu, Xiao; Zhou, Lin; Zheng, Shusen.Genetic Polymorphism of B7-H3 is Not Associated with HCC Incidence of LT Recipients in Han Chinese Population.Joint International Congress of ILTS, ELITA and LICAGE, 2014 to 2014-06-07.
[24]Lu, Di; Xu, Xiao; Zheng, Shusen.The Phospholipase A2 Domain of Peroxiredoxin 6 Plays a Critical Tumor-Suppressing Role in the Carcinogenesis and Recurrence of Hepatocellular Carcinoma.Joint International Congress of ILTS, ELITA and LICAGE, 2014 to 2014-06-07.
[25]Xu Xiao; Lu Di; Ling Qi; Wei Xuyong; Wu Jian; Zhou Lin; Yan Sheng; Wu Liming; Geng Lei; Ke Qinghong; Gao Feng; Tu Zhenhua; Wang Weilin; Zhang Min; Shen Yan; Xie Haiyang; Jiang Weishi; Wang Haibo; Zheng Shusen.Liver Transplantation for Hepatocellular Carcinoma Beyond the Milan Criteria.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 to 2014-06-07.
[26]Wei Xuyong; Xu Xiao; Xie Haiyang; Ling Qi; Lu Di; Wang Jianguo; Zhou Lin; Zheng Shushen.Clinical Significance of Serum Aminoacylase 1 Expression in Human Hepatocellular Carcinoma and Liver Transplantation.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 to 2014-06-07.
[27]Wang Kai; Xu Xiao; Ling Qi; Lu Di; Xiang Penghui; Wang Chao; Zheng Shusen.Association between Donor Liver LXR Gene Polymorphisms and Cholesterol Disarrangement after Liver Transplantation in a Chinese Han Population.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 to 2014-06-07.
[28]Wang Jianguo; Xu Xiao; Wei Xuyong; Lu Di; Xie Haiyang; Lin Qi; Zhou Lin; Zheng Shusen.Quantitative Proteomic Analysis Identified CAPS as a Novel Potential Biomarker for Early Detection of HBV-Relate Hepatocellular Carcinoma.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 to 2014-06-07.
[29]Ling Qi; Xu Xiao; Wang Kai; Xiang Penghui; Zhang Xuanyu; Wang Zhuoyi; Zhuang,Li; Zheng Shusen.Effect of Donor Hepatic PPAR alpha Gene Polymorphisms on Glucose and Lipid Disorders after Liver Transplantation.Joint International Congress of ILTS, ELITA and LICAGE, 2014-06-04 to 2014-06-07.
[30]葉于富,吳健,徐驍,嚴盛,俞軍,耿磊... & 鄭樹森. (2014). ~(18)F-FDG PET-CT在預(yù)測肝癌肝移植術(shù)后腫瘤復(fù)發(fā)及判斷預(yù)后中的價值研究. (eds.) 2014年浙江省外科學(xué)學(xué)術(shù)年會論文匯編 (pp.24).
[31]Xie Qinfen; Xu Xiao; Wang Kai; Tu Zhenliang; Hu Jian; Zhuang Li; Yu Jun; Zheng Shusen.Outcome of Pulmonary Metastasectomy after Liver Transplantation for Hepatocellular Carcinoma: Hangzhou Experience.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[32]Ling Qi; Xu Xiao; Dong Fengqin; Geng Lei; Liu Zhikun; Xie Haiyang; Zhou Lin; Zheng Shusen.Associations between TCF7L2 Gene Polymorphisms and the Risks for Hepatogenous Diabetes and Hepatocellular Carcinoma in Cirrhotic Patients.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[33]Xie Haiyang; Wei Bajin; Xu Xiao; Zhou Lin; Zhu Lixian; Yao Jia; Zheng Shusen.The Association between Polymorphisms of TLR3 Gene and HBV Related HCC in Liver Transplant Recipients.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[34]Wei Qiang; Xu Xiao; Ling Qi; Zhuang Li; Tu Zhenhua; Wu Jian; Zhang Min; Wang Weilin; Zheng Shusen.Steroid-Free Liver Transplantation for Hepatocellular Carcinoma: A Single-Center Experience.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[35]Wang Kai; Ling Qi; Xu Xiao; Wei Qiang; Chen Jun; Wu Liming; Zheng Shusen.Does Neutrophil to Lymphocyte Ratio Improve Hangzhou Criteria for Predicting Tumor Recurrence after Liver Transplantation?19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[36]Tu Zenhua; Xu Xiao; Zhang Min; Wang Weilin; Zheng Shusen.The Selection of Donors after Cardiac Death for Liver Transplantation: A Single Center's Experience from the Mainland of China.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[37]Zhang Mangli; Xu Jun; Wang Weilin; Zhang Min; Shen Yan; Zhou Lin; Xu Xiao; Wu Jian; Zhuang Li; Liu Xiangyan; Zheng Shusen.Microbial Epidemiology and Risk Factors of Infections in Liver Transplant Recipients: A 6-Year Single-Center Experience.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 To 2013-06-15.
[38]Xu Xiao; He Zenglei; Ling Qi; Wei Qiang; He Xiangxiang; Zhuang Li; Jiang Wenshi; Wang Haibo; Wang Weiling; Zheng Shusen*.Safety and Efficacy of Steroid-Free Liver Transplantation for Hepatocellular Carcinoma.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 to 2013-06-15.
[39]Xu Xiao; Ling Qi; Liu Zhikun; Guo Haijun; Xie Haiyang; Zhou Lin; Zheng Shusen.Donor miR-196a2 Polymorphism Is Associated with HCC Recurrence after Liver Transplantation.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 to 2013-06-15.
[40]Lu Di; Xu Xiao; Yang Jiayin; Zhong Lin; Ling Qi; Yan Lvnan; Peng Zhihai; Zheng Shusen*.Hangzhou Criteria in Liver Transplantation for Hepatocellular Carcinoma: A Multi-Center Validation Study.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 to 2013-06-15.
[41]Wei Xuyong; Xu Xiao; Liu Zhikun; Guo Haijun; Xie Haiyang; Zhou Lin; Zheng Shusen*.Proteomics-Based Identification of Tumor Suppressor Role for Aminoacylase 1 in Hepatocellular Carcinoma.19th Annual International Congress of the International-Liver-Transplantation-Society (ILTS), 2013-06-12 to 2013-06-15.
[42]謝琴芬, 徐驍, 汪愷, 屠振良, 胡堅 & 鄭樹森. (2013). 肝癌肝移植術(shù)后肺轉(zhuǎn)移灶切除療效分析:杭州經(jīng)驗. (eds.) 2013年浙江省外科學(xué)學(xué)術(shù)年會論文匯編 (pp.132).
[43]謝琴芬, 徐驍, 汪愷, 屠振良, 胡堅 & 鄭樹森. (2013). 肝癌肝移植術(shù)后肺轉(zhuǎn)移灶切除療效分析. (eds.) 2013中國器官移植大會論文匯編 (pp.82-83).
[44]謝海洋,徐驍,吳健,馮曉文,曹國強,陳雷鳴... & 鄭樹森. (2013). 肝癌及肝臟移植樣本庫的信息化管理及規(guī)范化應(yīng)用. (eds.) 2013中國器官移植大會論文匯編 (pp.465).
[45]郭海軍,徐驍,魏緒勇,凌琪,劉治坤,汪凱... & 鄭樹森. (2013). ALDOB在肝細胞肝癌中的作用. (eds.) 2013中國器官移植大會論文匯編 (pp.467).
[46]莊潤周,徐驍,楊家印,鐘林,魯?shù)?屠振華... & 鄭樹森. (2013). 杭州標(biāo)準適用于肝癌肝移植經(jīng)驗總結(jié). (eds.) 2013中國器官移植大會論文匯編 (pp.133-134).
[47]朱陽波, 高峰, 徐驍 & 鄭樹森. (2013). 小肝癌肝移植患者中微血管侵犯對腫瘤術(shù)后復(fù)發(fā)及預(yù)后的相關(guān)性研究. (eds.) 2013中國器官移植大會論文匯編 (pp.146-147).
[48]魏緒勇, 徐驍, 王建國, 李捷, 謝海洋, 周琳 & 鄭樹森. (2013). 細胞內(nèi)氯離子通道蛋白1蛋白表達與肝癌侵襲轉(zhuǎn)移的關(guān)系. (eds.) 2013中國器官移植大會論文匯編 (pp.489).
[49]Wei Xuyong; Xu Xiao; Ling Qi; Wei Qiang; Liu Xiaoli; Guo Haijun; Zhuang Li; Chen Jiajia; Xia Qi; Xie Haiyang; Wu Jian; Zheng Shusen; Li Lanjuan.Downgrading MELD Improves the Outcome after Liver Transplantation in Patients with Acute-on-Chronic Hepatitis B Liver Failure.18th Annual International Congress on ILTS, 2012-05-16 to 2012-05-19.
[50]Ling Qi; Xu Xiao; Wang Kai; Liu Zhikun; Lu Di; Jiang Wenshi; He Xiangxiang; Wang Haibo; Zhang Min; Zheng Shusen.Major Influence of Renal Function on Hyperlipidemia after Living Donor Liver Transplantation.18th Annual International Congress on ILTS, 2012-05-16 to 2012-05-19.
[51]Wei Qiang; Xu Xiao; Ling Qi; Wei Xuyong; Zhuang Li; Jiang Wenshi; He Xiangxiang; Wang Haibo; Wang Weilin; Zhang Min; Zheng Shusen*.PMPM: A Good Predict Indictor for Liver Transplantation Recipients for Benign End-Stage Liver Disease.18th Annual International Congress on ILTS, 2012-05-16 to 2012-05-19.
[52]Xu Xiao; Ling Qi; Jiang Wenshi; He Xiangxiang; Wang Haibo; Wang Weilin; Zhang Min; Zhou Lin; Zheng Shusen.Predicting Survival Following Liver Transplantation in the MELD Era.18th Annual International Congress on ILTS, 2012-05-16 to 2012-05-19.
[53]Lu Di; Xu Xiao; Ling Qi; Wang Kai; Wang Weilin; Zhang Min; Shen Yan; Xie Haiyang; Zhou Lin; Zheng Shusen.Contemporaneous Portal and Hepatic Artery Revascularization Protocol Is Assiociated with Lower Risk of Biliary Complication after Liver Transplantation.18th Annual International Congress on ILTS, 2012-05-16 to 2012-05-19.
[54]劉治坤,郭海軍,蘇蓉,宋文峰,沈克震,宋朋紅,徐驍... & 鄭樹森. (2012). TFCP2促進肝癌轉(zhuǎn)移復(fù)發(fā)的分子機制. (eds.) 2012年浙江省外科學(xué)學(xué)術(shù)年會論文集 (pp.75).
[55]郭海軍,宋朋紅,沈克震,殷勝勇,陳雷鳴,蘇蓉,徐驍... & 鄭樹森. (2012). ZIP4的高表達促進腫瘤的生長并且預(yù)示著肝癌病人預(yù)后不良. (eds.) 2012年浙江省外科學(xué)學(xué)術(shù)年會論文集 (pp.76).
[56]魏緒勇,王建國,馮曉文,王雁,曹國強,陳海,徐驍... & 鄭樹森. (2012). 肝癌組織中氨基酰化酶-1表達及作用. (eds.) 2012年浙江省外科學(xué)學(xué)術(shù)年會論文集 (pp.94-95).
[57]吳李鳴,周琳,徐軍,魏巴金,成俊,徐驍... & 鄭樹森. (2012). 細胞因子基因多態(tài)性和肝癌肝移植術(shù)后腫瘤復(fù)發(fā)風(fēng)險的相關(guān)性研究. (eds.) 2012中國器官移植大會論文匯編 (pp.392).
[58]魏緒勇,王建國,馮曉文,王雁,曹國強,陳海,徐驍... & 鄭樹森. (2012). 肝癌組織中氨基酰化酶-1表達及作用. (eds.) 2012中國器官移植大會論文匯編 (pp.381-382).
[59]劉治坤,郭海軍,蘇蓉,宋文峰,沈克震,宋朋紅,徐驍... & 鄭樹森. (2012). TFCP2促進肝癌轉(zhuǎn)移復(fù)發(fā)的分子機制. (eds.) 2012中國器官移植大會論文匯編 (pp.384).
[60]郭海軍,陳海,陳雷鳴,蘇蓉,馮曉文,柯慶宏,徐驍... & 鄭樹森. (2012). 肝細胞肝癌中ZIP4的表達及其臨床意義. (eds.) 2012中國器官移植大會論文匯編 (pp.393).
[61]王建國, 徐驍, 謝海洋, 蘇蓉, 宋文峰, 周琳 & 鄭樹森. (2012). DCP與AFP在肝癌診斷及肝癌肝移植預(yù)后中作用. (eds.) 2012中國器官移植大會論文匯編 (pp.67).
[62]Xu Xiao; Ling Qi; Wang Kai; Zhou Lin; Zheng Shusen*.Post-Transplant Hyperlipidemia in Living Donor Liver Transplantation: Hangzhou Experience.Joint International Congress of ILTS, ELITA, and LICAGE, 2011-06-22 to 2011-06-25.
[63]Xie Qinfen; Xu Xiao; Zheng Shusen.Outcome of Mycophenolate Mofetil Intolerant Liver Transplant Recipients: Hangzhou Experience.Joint International Congress of ILTS, ELITA, and LICAGE, 2011-06-22 to 2011-06-25.
[64]Wu Liming; Yang Zhe; Zhou Lin; Zhang Feng; Xie Haiyang; Feng Xiaowen; Wu Jian; Xu Xiao; Zheng Shusen.Identification of Histone Deacetylase 3 as a Biomarker for Tumor Recurrence Following Liver Transplantation in Hepatocellular Carcinoma.Joint International Congress of ILTS, ELITA, and LICAGE, 2011-06-22 to 2011-06-25.
[65]Wei Oiang; Xu Xiao; Zhou Bin; Wei Xuyong; Xie Haiyang; Zheng Shusen.The Impact of Intra-Operative Cholangiography and Parenchymal Resection on Donor Liver Function in Living Donor Liver Transplantation.Joint International Congress of ILTS, ELITA, and LICAGE, 2011-06-22 to 2011-06-25.
[66]Ling Qi; Xu Xiao; Chen Jun; He Zenglei; Xie Haiyang; Zheng Shusen.Diabetes Mellitus and Hepatocellular Carcinoma Recurrence after Liver Transplantation.Joint International Congress of ILTS, ELITA, and LICAGE, 2011-06-22 to 2011-06-25.
[67]Ling Qi; Xu Xiao; Ke Qinghong; Zhuang Li; Wang Zhuoyi; Zhang Min; Zheng Shusen.Tight Blood Glucose Control in Diabetic Patients with Hepatitis B Virus-Related Liver Disease for Liver Transplantation.16th Annual Congress of the International-Liver-Transplantation-Society, 2010-06-16 To 2010-06-19.
[68]Xu Xiao; Ling Qi; Wu Jian; Zhou Lin; Zheng ShuSen.AN EFFECTIVE MODEL FOR PREDICTING EARLY ACUTE KIDNEY INJURY FOLLOWING LIVER TRANSPLANTATION.15th Annual Congress of the International-Liver-Transplantation-Society, 2009-07-08 To 2009-07-11.
[69]Zheng, Shusen; Liang, Tingbo; Wang, Weilin; Shen, Yan; Zhang, Min; Wu, Jian; Xu, Xiao.Liver transplantation for hepatocellular carcinoma: prognostic analysis of 187 cases
[70]蔣智軍,王偉林,梁廷波,沈巖,張珉,吳健... & 鄭樹森. (2008). 肝臟星狀細胞在肝移植免疫耐受誘導(dǎo)機制中的作用. (eds.) 2008年浙江省外科學(xué)術(shù)年會論文匯編 (pp.236).
[71]蔣智軍,馮曉寧,梁廷波,王偉林,沈巖,張珉... & 鄭樹森. (2008). 中國人群中受體CTLA4+49G/G基因型與肝移植后乙肝復(fù)發(fā)幾率降低有關(guān). (eds.) 2008年浙江省外科學(xué)術(shù)年會論文匯編 (pp.248).
[72]鄭樹森, 徐驍, 衛(wèi)強 & 何增磊. (2008). 肝癌肝移植受者選擇標(biāo)準. (eds.) 2008年浙江省外科學(xué)術(shù)年會論文匯編 (pp.161).
[73]鄭樹森,陳峻,王偉林,張珉,沈巖,吳健... & 嚴盛. (2008). 肝細胞癌肝移植術(shù)后復(fù)發(fā)和轉(zhuǎn)移:單中心經(jīng)驗. (eds.) 2008年浙江省外科學(xué)術(shù)年會論文匯編 (pp.181-182).
[74]鄭樹森, 徐驍, 張啟逸, 王偉林, 吳健 & 俞軍. (2007). 成人活體肝移植供體評估杭州經(jīng)驗:附116例供體候選者篩選報告. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.43).
[75]鄭樹森, 徐驍, 馮曉寧, 吳健 & 俞軍. (2007). 成人活體部分肝移植術(shù)后早期他克莫司應(yīng)用經(jīng)驗分析. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.63).
[76]鄭樹森, 徐驍, 高峰, 謝海洋 & 周琳. (2007). 脂肪變性供肝的臨床應(yīng)用體會. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.63-64).
[77]鄭樹森, 徐驍, 張宇, 俞軍, 王偉林 & 彭志毅. (2007). 成人活體右半肝移植中移植肝體積估測的臨床意義. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.64).
[78]吳健,王偉林,張珉,沈巖,梁廷波,俞鵬飛... & 鄭樹森. (2007). 右半肝活體肝移植中肝中靜脈分支的處理. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.79-80).
[79]徐驍, 凌琪, 吳健 & 鄭樹森. (2007). 肝移植治療并發(fā)肝腎綜合征的肝硬化病人預(yù)后分析. (eds.) 2007年浙江省外科學(xué)學(xué)術(shù)會議論文匯編 (pp.80-81).
[80]吳健,王偉林,張珉,沈巖,梁廷波,俞鵬飛... & 鄭樹森. (2007). 右半肝活體肝移植中肝中靜脈分支的處理. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.145-146).
[81]鄭樹森, 徐驍, 張宇, 俞軍, 王偉林 & 彭志毅. (2007). 成人活體右半肝移植中移植肝體積估測的臨床意義. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.149).
[82]蔣智軍,馮曉寧,梁廷波,王偉林,沈巖,張珉... & 鄭樹森. (2007). 中國人群中受體CTLA4 +49 G/G基因型與肝移植后乙肝復(fù)發(fā)幾率降低有關(guān). (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.352).
[83]俞志勇, 俞軍, 徐驍 & 鄭樹森. (2007). 活體肝移植供體圍手術(shù)期并發(fā)癥的回顧性分析. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.355).
[84]鄭樹森, 徐驍, 張啟逸, 王偉林, 吳健 & 俞軍. (2007). 成人活體右半肝移植供體評估杭州經(jīng)驗:附90例供體候選者篩選報告. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.355).
[85]鄭樹森, 徐驍, 高峰, 謝海洋 & 周琳. (2007). 脂肪變性供肝的臨床應(yīng)用體會. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.357).
[86]徐驍, 凌琪, 吳健 & 鄭樹森. (2007). 肝移植治療并發(fā)肝腎綜合征的肝硬化病人預(yù)后分析. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.388).
[87]鄭樹森, 徐驍, 馮曉寧, 吳健 & 俞軍. (2007). 成人活體部分肝移植術(shù)后早期他克莫司應(yīng)用經(jīng)驗分析. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.388).
[88]鄭樹森,胡振華,王偉林,梁廷波,張珉,沈巖... & 盧安衛(wèi). (2007). 兒童活體肝移植診治經(jīng)驗. (eds.) 2007中國外科周暨第16屆亞洲外科年會論文摘要集 (pp.149-150).
[89]鄭樹森, 徐驍, 張啟逸, 王偉林, 吳健 & 俞軍. (2007). 成人活體右半肝移植供體評估杭州經(jīng)驗:附90例供體候選者篩選報告. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.37-38).
[90]鄭樹森, 徐驍, 張宇, 俞軍, 王偉林 & 彭志毅. (2007). 成人活體右半肝移植中移植肝體積估測的臨床意義. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.38-39).
[91]徐驍, 凌琪, 吳健 & 鄭樹森. (2007). 肝移植治療并發(fā)肝腎綜合征的肝硬化病人預(yù)后分析. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.48).
[92]俞志勇, 俞軍, 徐驍 & 鄭樹森. (2007). 活體肝移植供體圍手術(shù)期并發(fā)癥的回顧性分析. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.49-50).
[93]吳健,王偉林,張珉,沈巖,梁廷波,俞鵬飛... & 鄭樹森. (2007). 右半肝活體肝移植中肝中靜脈分支的處理. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.54-55).
[94]鄭樹森, 徐驍, 高峰, 謝海洋 & 周琳. (2007). 脂肪變性供肝的臨床應(yīng)用體會. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.55).
[95]蔣智軍,馮曉寧,梁廷波,王偉林,沈巖,張珉... & 鄭樹森. (2007). 中國人群中受體CTLA4+49 G/G基因型與肝移植后乙肝復(fù)發(fā)幾率降低有關(guān). (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.95).
[96]鄭樹森,胡振華,王偉林,梁廷波,張珉,沈巖... & 盧安衛(wèi). (2007). 兒童活體肝移植診治經(jīng)驗. (eds.) 2007年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.38).
[97]鄭樹森, 梁廷波, 王偉林, 沈巖, 張珉, 徐驍 & 吳健. (2006). 原位肝移植術(shù)后膽道并發(fā)癥的防治. (eds.) 第八屆國際治療內(nèi)鏡和消化疾病學(xué)術(shù)會議論文匯編 (pp.241-242).
[98]邵浙新, 徐驍, 鄭樹森, 梁廷波, 柯慶宏 & 馬怡平. (2005). 肝細胞癌肝移植術(shù)后甲胎蛋白變化與腫瘤復(fù)發(fā). (eds.) 2005年浙江省感染病、肝病學(xué)術(shù)會議論文匯編 (pp.452-454).
[99]鄭樹森, 郭華, 梁廷波, 徐驍, 沈巖, 王偉林 & 張珉. (2005). 肝移植術(shù)后淋巴組織增生性疾病一例報告. (eds.) 2005年浙江省外科學(xué)術(shù)會議論文匯編 (pp.118).
[100]鄭樹森, 郭華, 梁廷波, 徐驍, 沈巖, 王偉林 & 張珉. (2005). 肝移植術(shù)后淋巴組織增生性疾病1例報告. (eds.) 2005年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.64-65).
[101]鄭樹森,王偉林,梁廷波,徐驍,金晶,沈巖... & 吳健. (2005). 急診肝移植救治良性終末期肝病. (eds.) 2005年浙江省器官移植學(xué)術(shù)會議論文匯編 (pp.102).
[102]鄭樹森, 徐驍, 梁廷波, 陳海勇, 王偉林, 夏偉良 & 吳健. (2005). 肝移植術(shù)后早期肝動脈血供不良與膽道并發(fā)癥. (eds.) 中華醫(yī)學(xué)會第十二次全國病毒性肝炎及肝病學(xué)術(shù)會議論文匯編 (pp.298).
[103]鄭樹森, 徐驍, 梁廷波, 陳海勇, 王偉林, 夏偉良 & 吳健. (2005). 肝移植術(shù)后早期肝動脈血供不良與膽道并發(fā)癥. (eds.) 第三屆國際暨全國肝衰竭與人工肝學(xué)術(shù)會議論文集 (pp.499-505).
[104]鄭樹森, 徐驍, 胡振華, 梁廷波, 吳健, 張珉 & 滕曉軍. (2004). 胰腺實性-假乳頭狀瘤的臨床診治:附國內(nèi)文獻分析. (eds.) 2004年浙江省外科學(xué)學(xué)術(shù)年會論文匯編 (pp.96-97).
[105]黃東勝,徐驍,李啟勇,鄭樹森,王偉林,梁廷波... & 蔣江營. (2004). 胰島素瘤的診斷與治療(附49例報告). (eds.) 中華醫(yī)學(xué)會第10屆全國胰腺外科學(xué)術(shù)研討會論文匯編 (pp.177-178).
[106]鄭樹森,吳健,黃東勝,王偉林,梁延波,沈巖... & 徐驍. (2001). 肝臟移植在治療肝臟惡性腫瘤中的作用. (eds.) 第八屆全國肝癌學(xué)術(shù)會議論文匯編 (pp.39).
所獲榮譽:
1. 2003年,獲獲石華玉醫(yī)學(xué)專項青年醫(yī)生獎。
2. 2010年,入選浙江省“新世紀151人才工程”第二層次培養(yǎng)人選。
3. 2002年,入選教育部“新世紀優(yōu)秀人才支持計劃”。
4. 2014年,教育部“長江學(xué)者獎勵計劃”特聘教授。(The Yangtze River Scholar Distinguished Professor of Ministry of Education)。
5. 2014年,科技部“中青年科技創(chuàng)新領(lǐng)軍人才”。(Young and Middle-Aged Leading Scientists, Engineers and Innovators of Ministry of Science and Technology)。
6. 2016年,國家“**計劃”科技創(chuàng)新領(lǐng)軍人才(Winner of The Ten Thousand Talent Program)。
7.2016年, 國家杰出青年科學(xué)基金獲得者(Winner of The National Natural Science Fund for Distinguished Young Scholar)。
8. 2020年,浙江大學(xué)求是特聘教授(Qiushi Distinguished Professor of Zhejiang University)。
9. 入選浙江省衛(wèi)生高層次創(chuàng)新人才。
10. 第六屆“吳孟超醫(yī)學(xué)青年基金獎”獲得者。
11. 多次獲得浙江大學(xué)先進工作者與浙江大學(xué)優(yōu)秀班主任榮譽稱號。
所獲獎勵:
1. 2015年,國家科技進步創(chuàng)新團隊獎(National Innovation Team Award for Scientific and Technological Progress)。
2. 2013年,國家科技進步一等獎(National First Class Prize for Scientific and Technological Progress)(重癥肝病診治的理論創(chuàng)新與技術(shù)突破,7/15)。
3. 2018年,國家教學(xué)成果二等獎 (National Second Class Prize for Teaching Achievement )。
4. 2018年,中國腫瘤青年科學(xué)家獎(China Oncology Research Award for Distinguished Young Scholar)。
5. 2012年,吳孟超醫(yī)學(xué)青年基金獎(Winner of Shanghai Wu Mengchao Medical Science Foundation)。
6. 2005、2007、2009、2013年,浙江省科學(xué)技術(shù)一等獎(First Class Prize for Science and Technology of Zhejiang Province)。
7. 2008年,國家科技進步二等獎(National Second Class Prize for Scientific and Technological Progress),(肝移植技術(shù)創(chuàng)新體系的建立與推廣應(yīng)用,9/15)。
8. 2002年,全國器官移植學(xué)術(shù)會議優(yōu)秀論文獎。
9. 2004年,教育部科技成果。
10. 榮獲浙江省醫(yī)藥衛(wèi)生科技創(chuàng)新一等獎。
徐驍:惟日孜孜 無敢逸豫
他是浙江大學(xué)外科學(xué)教授、博士生導(dǎo)師,浙江大學(xué)附屬第一醫(yī)院院長助理、醫(yī)務(wù)部主任、肝膽胰外科副主任、紹興第二醫(yī)院(浙大一院紹興分院)副院長,是教育部“新世紀優(yōu)秀人才支持計劃”和第六屆“吳孟超醫(yī)學(xué)青年基金獎”獲得者。主持 863 課題、973 課題和國家自然科學(xué)基金等5項國家級科研項目。
他是中國醫(yī)師協(xié)會器官移植醫(yī)師分會常委兼總干事,中華醫(yī)學(xué)會器官移植學(xué)分會委員、肝移植學(xué)組委員,中華醫(yī)學(xué)會外科學(xué)分會肝臟外科學(xué)組委員。
這些頭銜與眼前這位身著白大衣,臉上掛著暖暖微笑的儒雅男子聯(lián)系在一起,正是 “恰同學(xué)少年,風(fēng)華正茂;書生意氣,揮斥方遒”這句詩詞的完美詮釋。
徐驍教授剛做完一臺手術(shù),顧不得疲憊便匆匆來到采訪現(xiàn)場。
在挑戰(zhàn)中感受醫(yī)生責(zé)任和快樂
患者重獲健康是我最大的快樂。
徐驍?shù)母改妇巧鲜兰o六十年代畢業(yè)的大學(xué)生,作為新中國培養(yǎng)的較早一批科技工作者,他們對醫(yī)生這個帶有“懸壺濟世、救死扶傷、解除病痛”色彩的職業(yè)充滿尊敬,徐驍自小就能感受到父母的這份尊敬,這份尊敬也在他的心里生根發(fā)芽。“高考我所有志愿都是醫(yī)學(xué)專業(yè)。”對于自己當(dāng)時的執(zhí)著,他充滿自豪感。
他一直覺得自己是幸運的,當(dāng)他面臨選擇專業(yè)和導(dǎo)師的時候,正值器官移植、肝癌、胰腺癌等手術(shù)在浙江大學(xué)附屬第一醫(yī)院(以下簡稱“浙大一院”)開展的關(guān)鍵時期。1993年鄭樹森院士做了浙江省第一例肝臟移植手術(shù),掀起了中國第二次肝移植浪潮。“1995年我選導(dǎo)師的時候,浙大一院的肝移植工作已經(jīng)走在全國前列,這給了我很大的鼓舞,鄭院士的開創(chuàng)性工作給了我很大啟示和引領(lǐng),也吸引我們一群年輕人加入到鄭院士的團隊。”
說起他的導(dǎo)師,徐驍總是掩飾不住的尊敬與感激。“我能在不到30歲就到香港大學(xué)外科學(xué)系瑪麗醫(yī)院進修,完全是鄭院士給予的機會。”在瑪麗醫(yī)院的學(xué)習(xí),徐驍印象最深的是其所在實驗室掛著的一張照片,那是上個世紀90年代初鄭樹森院士在香港做博士后時在實驗室的工作照。鄭院士作為第一助手參加了香港第一例肝移植手術(shù)并獲成功,該手術(shù)成為當(dāng)年香港十大新聞。而成功的背后則是鄭院士在香港艱苦卓絕地開展了400例豬的肝臟移植手術(shù)。“我2001年去香港時,差不多已過了10年,那張照片一直掛在那里,時刻激勵著我勤奮向上。” 如今,他跟隨著鄭院士帶領(lǐng)的肝臟移植技術(shù)團隊,走到哪里,他們的技術(shù)就帶到哪里。而肝移植技術(shù)的最大受益者,就是全中國乃至全世界的老百姓。
肝膽胰外科是大外科手術(shù)中最具挑戰(zhàn)性的領(lǐng)域,對醫(yī)生的體力和腦力要求都是極為苛刻。“在我還是住院醫(yī)師、主治醫(yī)師的時候,曾有很多個除夕夜,當(dāng)我們做完手術(shù),聽到手術(shù)室外面?zhèn)鱽肀夼诼暡鸥杏X到,哦,過年了。” 徐驍深愛著這份極具挑戰(zhàn)的職業(yè),看著患者重獲健康,是他感覺最快樂的一件事。
醫(yī)患溝通中醫(yī)生是主動方
從患者的角度去感同身受,醫(yī)患間的交流才能更順暢。
做好一個外科醫(yī)生,并不僅僅是完成一臺漂亮的手術(shù),更需要做到與患者共同對抗病魔,因此醫(yī)患間的理解和溝通更為必要。“我們治療的對象是活生生的患者。他想到了什么、在擔(dān)心什么,如果醫(yī)生能去感同身受,多替他們考慮,那么醫(yī)患之間的交流才能更加順暢。”徐驍認為,醫(yī)患溝通,醫(yī)生應(yīng)該擔(dān)當(dāng)主動角色。
目前像浙大一院每天都有超萬人的門診量,這些患者中有普通疾病,也有疑難雜癥。然而醫(yī)療資源有限,醫(yī)生很難做到把足夠的時間和精力留給每一位患者。“我的專家門診號一般嚴格限制在一定數(shù)目。對于近期來復(fù)診的患者,我會建議他們只掛普通號。上午8:00~11:00集中精力診治掛專家號的患者,11:00以后的時間就留給復(fù)診普通號患者,回答咨詢,并提供后續(xù)治療方案。”徐驍?shù)倪@項舉措,對于減輕患者的經(jīng)濟負擔(dān)和節(jié)約患者的就診時間,都是起著立竿見影的效果。
臨床醫(yī)生應(yīng)重視科研的臨床轉(zhuǎn)化
醫(yī)生若只是機械重復(fù)前人工作,很多臨床問題就永遠無法突破。
“鄭院士一直教導(dǎo)我們,患者是最好的老師。從查房、決定治療方案、術(shù)前準備,到手術(shù)時的團隊配合、術(shù)后并發(fā)癥防治及術(shù)后輔助性治療,管理一個患者可以學(xué)到很多。尤其在面對疑難病例和并發(fā)癥的處理時更應(yīng)迎難而上,不斷積累經(jīng)驗,以便更好地救治患者。”
徐驍深刻感受到,要成為攻克疾病的醫(yī)生,除了積累經(jīng)驗,還應(yīng)該有科研思路作為支撐。“這些科研思路來源于臨床實踐。例如,臨床實踐中發(fā)現(xiàn),同樣是胰腺癌患者,經(jīng)過放化療,只有部分患者腫瘤明顯減小,而有些沒有變化甚至有進展。這提示同一種腫瘤不同分子分型對放化療的敏感度不同。如果知道腫瘤特殊分子分型,就可以進行針對性治療,提高療效并為患者減少痛苦和經(jīng)濟損失。此外,很多肝癌患者就診時已為中晚期,缺乏早期診斷的敏感檢測手段。”“若醫(yī)生只是機械地重復(fù)前人的工作,這些問題就永遠無法突破。因此,臨床醫(yī)生需要做科研,且選題要來源于臨床,這樣才能更好服務(wù)于臨床。”
秉承這些理念,徐驍進行了富有成效的研究。2006年,他遠赴德國基爾大學(xué)分子腫瘤中心開展蛋白組學(xué)研究,歸國后在鄭院士的支持下組建肝病蛋白組學(xué)實驗室;2012年,徐驍作為項目負責(zé)人,聯(lián)合國內(nèi)6所大學(xué)和科研單位,成功申請863課題“肝病發(fā)生發(fā)展與肝癌轉(zhuǎn)移復(fù)發(fā)的蛋白質(zhì)分子標(biāo)志物的臨床應(yīng)用研究”。目前,已研究發(fā)現(xiàn)并驗證了一批肝病發(fā)生發(fā)展的關(guān)鍵分子標(biāo)志物。
鑒于在肝病蛋白組學(xué)領(lǐng)域的成就,徐驍?shù)膶W(xué)術(shù)論文多次被在西班牙、美國和澳大利亞召開的國際肝移植協(xié)會年會收錄。2014年6月受邀在英國倫敦第20屆國際肝移植協(xié)會年會上進行學(xué)術(shù)報告,引起肝移植學(xué)界廣泛關(guān)注。
忘我工作 只爭朝夕
“辛苦倒是說不上,只是覺得時間不夠用,希望能做更多的工作去幫助患者戰(zhàn)勝疾病。”
作為博士生導(dǎo)師,徐驍非常推崇他的老師鄭院士的治學(xué)之道,也十分重視對學(xué)生們的帶教和指導(dǎo)。他關(guān)心學(xué)生們的生活,指導(dǎo)他們在日常學(xué)習(xí)和工作中提高醫(yī)者榮譽感和使命感,鼓勵他們熱愛醫(yī)學(xué)工作,把更多精力放在學(xué)習(xí)和科研上;以身作則,“授之以漁”,鼓勵學(xué)生多看文獻,增強創(chuàng)新意識,努力爭取國際會議中作大會報告的機會等。“亦師亦友的時候,學(xué)生的進步最快。”他笑言,而“亦師亦友”也正是學(xué)生們對他的普遍評價。
中國醫(yī)師協(xié)會器官移植醫(yī)師分會常委兼總干事,中華醫(yī)學(xué)會器官移植學(xué)分會委員、肝移植學(xué)組委員,中華醫(yī)學(xué)會外科學(xué)分會肝臟外科學(xué)組委員,是徐驍?shù)膶W(xué)術(shù)身份。“我非常有感觸,最近10余年來,中國的器官移植事業(yè)在鄭樹森院士的領(lǐng)導(dǎo)下,取得了巨大的進步。我們將致力于推動中國器官移植行業(yè)規(guī)范、標(biāo)準、指南、專家共識的建立和完善,我為能在這些工作中盡自己的綿薄之力而感到高興和自豪。”
筆者所聞所見,深有感觸:“這樣工作真是太辛苦了!”徐驍教授感慨道:“辛苦倒是說不上,只是覺得時間不夠用,希望能做更多的工作去幫助患者戰(zhàn)勝疾病。”
來源:醫(yī)師報 2014-09-09
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