| 張高榮1,2, 黃錫山2, 黃 艷2, 賴紅芳1, 王愛娟1, 李 俊2* |
| 1. 河池學院 化學與生物工程學院, 微生物及植物資源開發利用廣西高校重點實驗室, 廣西 宜州 546300;2. 廣西師范大學 化學與藥學學院, 省部共建藥用資源化學與藥物分子工程國家重點實驗室, 廣西 桂林 541000 |
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| 摘要: |
| 為研究刺桑(Taxotrophis ilicifolia)皮正丁醇部位的化學成分,該研究采用硅膠、ODS、Sephadex LH-20、反相半制備高效液相等色譜法對刺桑皮正丁醇萃取部位進行分離純化,并綜合理化性質及波譜數據鑒定其化合物的結構。結果表明:從刺桑皮正丁醇萃取物中分離得到16個化合物,分別鑒定為icariside E5(1)、裂環異落葉松脂醇-9-O-β-吡喃葡萄糖苷(2)、2,4,6-三甲氧基苯酚-1-O-β-D-葡萄糖苷(3)、9-O-β-glucopyranosyl trans-cinnamyl alcohol(4)、3,4,5-三甲氧基苯酚-1-O-β-呋喃芹糖基-(1″→6')-β-吡喃葡萄糖苷(5)、3-羥基-4,5-二甲氧基苯酚-β-D-吡喃葡萄糖苷(6)、2,6-二甲氧基-4-羥基苯酚-1-O-β-D-吡喃葡萄糖苷(7)、isotachioside(8)、ficuscarpanoside A(9)、uridine(10)、methyl syringate 4-O-β-D-glucopyranoside(11)、3,4,5-三甲氧基苯酚-β-D-吡喃葡萄糖苷(12)、木犀草素(13)、人參皂苷Rg1(14)、(+)-lyonirenisol-3α-O-β-D-glucopyranoside(15)、myricetin 3-neohesperidoside(16)。所有化合物均為首次從該屬植物中分離得到。 |
| 關鍵詞: 刺桑, 化學成分, icariside E5, 裂環異落葉松脂醇-9-O-β-吡喃葡萄糖苷, 人參皂苷Rg1 |
| DOI：10.11931/guihaia.gxzw202112055 |
| 分類號:Q946 |
| 文章編號:1000-3142(2023)01-0165-09 |
| 基金項目:國家自然科學基金(216620040); 河池學院高層次人才科研項目(2021GCC018); 河池學院科研項目(2020XJYB007); 廣西高校中青年教師科研基礎能力提升項目(2022KY0611)。 |
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| Chemical constituents from the bark of n-BuOH fraction of Taxotrophis ilicifolia |
| ZHANG Gaorong1, 2, HUANG Xishan2, HUANG Yan2, LAI Hongfang1, Wang Aijuan1, LI Jun2 |
| Hospital of Traditional Chinese Medicine, Qinzhou 535099, China |
| Abstract: |
| To study the chemical constituents from the n-BuOH part of the bark of Taxotrophis ilicifolia, sixteen compounds were isolated and purified from the n-BuOH part of the bark of T. ilicifolia by means of various column chromatographic techniques, including silica gel, ODS, Sephadex LH-20 and semi-preparative RP-HPLC. The structures of the isolates were identified by physiochemical properties and spectral data. The results were as follows: The compounds were identified as icariside E5(1), secoisolariciresinol 9-O-β-glucopyranoside(2), 2,4,6-trimethoxyphenol-1-O-β-D-glycoside(3),9-O-β-glucopyranosyl trans-cinnamyl alcohol(4), 3,4,5-trimethoxyphenyl-1-O-β-apiofuranosyl-(1″→6')-β-glucopyranoside(5),3-hydroxy-4,5-dimethoxyphenyl-β-D-glucopyranoside(6), 2,6-dimethoxy-4- hydroxyphenol-1-O-β-D-glucopyranoside(7), isotachioside(8), ficuscarpanoside A(9), uridine(10), methyl syringate 4-O-β-D-glucopyranoside(11), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside(12), luteolin(13), ginsenoside Rg1(14),(+)-lyonirenisol-3α-O-β-D-glucopyranoside(15), myricetin 3-neohesperidoside(16). All compounds were isolated from plants of Taxotrophis for the first time. |
| Key words: Taxotrophis ilicifolia, chemical constituents, icariside E5, secoisolariciresinol 9-O-β-glucopyranoside, ginsenoside Rg1 |
刺桑皮正丁醇部位化學成分研究.pdf
